Prematurity and Sudden Unexpected Infant Deaths in the United States

Prematurity, a strong risk factor for sudden unexpected infant death (SUID), was addressed in recommendations by the American Academy of Pediatrics in 2011 for safe sleep education in NICUs. We documented associations between gestational age (GA) and SUID subsequent to these guidelines. Using the 20...

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Veröffentlicht in:Pediatrics (Evanston) 2017-07, Vol.140 (1), p.1
Hauptverfasser: Ostfeld, Barbara M, Schwartz-Soicher, Ofira, Reichman, Nancy E, Teitler, Julien O, Hegyi, Thomas
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creator Ostfeld, Barbara M
Schwartz-Soicher, Ofira
Reichman, Nancy E
Teitler, Julien O
Hegyi, Thomas
description Prematurity, a strong risk factor for sudden unexpected infant death (SUID), was addressed in recommendations by the American Academy of Pediatrics in 2011 for safe sleep education in NICUs. We documented associations between gestational age (GA) and SUID subsequent to these guidelines. Using the 2012-2013 US linked infant birth and death certificate period files, we documented rates per live births of sudden infant death syndrome, ill-defined and unspecified causes, accidental suffocation and strangulation in bed, and overall SUID by GA in postneonatal, out-of-hospital, and autopsied cases; compared survivors and cases; and estimated logistic regression models of associations between GA and SUID. SUID cases were more likely than survivors to be
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We documented associations between gestational age (GA) and SUID subsequent to these guidelines. Using the 2012-2013 US linked infant birth and death certificate period files, we documented rates per live births of sudden infant death syndrome, ill-defined and unspecified causes, accidental suffocation and strangulation in bed, and overall SUID by GA in postneonatal, out-of-hospital, and autopsied cases; compared survivors and cases; and estimated logistic regression models of associations between GA and SUID. SUID cases were more likely than survivors to be &lt;37 weeks' GA (22.61% vs 10.79%; &lt; .0001). SUID rates were 2.68, 1.94, 1.46, 1.16, 0.73, and 0.51 per 1000 live births for 24 to 27, 28 to 31, 32 to 33, 34 to 36, 37 to 38, and 39 to 42 weeks' GA, respectively. Logistic regression models additionally indicated declines in the risk for SUID as GA increased. Prenatal smoking, inadequate prenatal care, and demographics associated with poverty were strongly associated with SUID. Despite the 2011 American Academy of Pediatrics recommendations for increased safe sleep education in the NICUs, SUID rates were inversely associated with GA in 2012 to 2013, suggesting that risk of SUID associated with prematurity has multiple etiologies requiring continued investigation, including biological vulnerabilities and the efficacy of NICU education programs, and that strategies to reduce SUID should be multifaceted.</description><identifier>ISSN: 0031-4005</identifier><identifier>EISSN: 1098-4275</identifier><identifier>DOI: 10.1542/peds.2016-3334</identifier><identifier>PMID: 28759397</identifier><language>eng</language><publisher>United States: American Academy of Pediatrics</publisher><subject>Analysis ; Asphyxia ; Autopsies ; Cause of Death ; Company business management ; Complications and side effects ; Death ; Demographics ; Demography ; Economic conditions ; Economic forecasts ; Economic indicators ; Female ; Gestational Age ; Humans ; Infant ; Infant Mortality ; Infant, Newborn ; Infant, Premature ; Infants (Premature) ; Logistic Models ; Management ; Patient outcomes ; Pediatrics ; Poverty ; Practice guidelines (Medicine) ; Premature infants ; Prenatal care ; Prenatal drug exposure ; Regression analysis ; Risk Factors ; SIDS ; Sleep ; Smoking ; Statistical data ; Sudden Infant Death - epidemiology ; Sudden Infant Death - etiology ; Sudden infant death syndrome ; United States</subject><ispartof>Pediatrics (Evanston), 2017-07, Vol.140 (1), p.1</ispartof><rights>Copyright © 2017 by the American Academy of Pediatrics.</rights><rights>Copyright American Academy of Pediatrics Jul 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c401t-710e2aa5f7e7c1b19d114656ed64251913a9b0ec2ce678d12925b4a14262e0da3</citedby><cites>FETCH-LOGICAL-c401t-710e2aa5f7e7c1b19d114656ed64251913a9b0ec2ce678d12925b4a14262e0da3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28759397$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ostfeld, Barbara M</creatorcontrib><creatorcontrib>Schwartz-Soicher, Ofira</creatorcontrib><creatorcontrib>Reichman, Nancy E</creatorcontrib><creatorcontrib>Teitler, Julien O</creatorcontrib><creatorcontrib>Hegyi, Thomas</creatorcontrib><title>Prematurity and Sudden Unexpected Infant Deaths in the United States</title><title>Pediatrics (Evanston)</title><addtitle>Pediatrics</addtitle><description>Prematurity, a strong risk factor for sudden unexpected infant death (SUID), was addressed in recommendations by the American Academy of Pediatrics in 2011 for safe sleep education in NICUs. 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Despite the 2011 American Academy of Pediatrics recommendations for increased safe sleep education in the NICUs, SUID rates were inversely associated with GA in 2012 to 2013, suggesting that risk of SUID associated with prematurity has multiple etiologies requiring continued investigation, including biological vulnerabilities and the efficacy of NICU education programs, and that strategies to reduce SUID should be multifaceted.</description><subject>Analysis</subject><subject>Asphyxia</subject><subject>Autopsies</subject><subject>Cause of Death</subject><subject>Company business management</subject><subject>Complications and side effects</subject><subject>Death</subject><subject>Demographics</subject><subject>Demography</subject><subject>Economic conditions</subject><subject>Economic forecasts</subject><subject>Economic indicators</subject><subject>Female</subject><subject>Gestational Age</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant Mortality</subject><subject>Infant, Newborn</subject><subject>Infant, Premature</subject><subject>Infants (Premature)</subject><subject>Logistic Models</subject><subject>Management</subject><subject>Patient outcomes</subject><subject>Pediatrics</subject><subject>Poverty</subject><subject>Practice guidelines (Medicine)</subject><subject>Premature infants</subject><subject>Prenatal care</subject><subject>Prenatal drug exposure</subject><subject>Regression analysis</subject><subject>Risk Factors</subject><subject>SIDS</subject><subject>Sleep</subject><subject>Smoking</subject><subject>Statistical data</subject><subject>Sudden Infant Death - epidemiology</subject><subject>Sudden Infant Death - etiology</subject><subject>Sudden infant death syndrome</subject><subject>United States</subject><issn>0031-4005</issn><issn>1098-4275</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkU1LxDAQhoMoun5cPUrBi5eumXw0zVHWr4UFBfUcssmsVrrp2qSg_96UVQ-e5jDPO7zDQ8gp0ClIwS436OOUUahKzrnYIROgui4FU3KXTCjlUApK5QE5jPGdUiqkYvvkgNVKaq7VhFw_9ri2aeib9FXY4IunwXsMxUvAzw26hL6Yh5UNqbhGm95i0YQivWHeN-PuKdmE8ZjsrWwb8eRnHpGX25vn2X25eLibz64WpRMUUqmAIrNWrhQqB0vQHkBUskJfCSZBA7d6SdExh5WqPTDN5FJYEKxiSL3lR-Rie3fTdx8DxmTWTXTYtjZgN0QDOcBUnZ_P6Pk_9L0b-pDbjZRSWvOKZ6rcUq-2RdME14WEn8l1bYuvaHL52YO5ErquOVNQZ3665V3fxdjjymz6Zm37LwPUjD7M6MOMPszoIwfOfmoMyzX6P_xXAP8GUzKDdQ</recordid><startdate>201707</startdate><enddate>201707</enddate><creator>Ostfeld, Barbara M</creator><creator>Schwartz-Soicher, Ofira</creator><creator>Reichman, Nancy E</creator><creator>Teitler, Julien O</creator><creator>Hegyi, Thomas</creator><general>American Academy of Pediatrics</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>U9A</scope><scope>7X8</scope></search><sort><creationdate>201707</creationdate><title>Prematurity and Sudden Unexpected Infant Deaths in the United States</title><author>Ostfeld, Barbara M ; 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We documented associations between gestational age (GA) and SUID subsequent to these guidelines. Using the 2012-2013 US linked infant birth and death certificate period files, we documented rates per live births of sudden infant death syndrome, ill-defined and unspecified causes, accidental suffocation and strangulation in bed, and overall SUID by GA in postneonatal, out-of-hospital, and autopsied cases; compared survivors and cases; and estimated logistic regression models of associations between GA and SUID. SUID cases were more likely than survivors to be &lt;37 weeks' GA (22.61% vs 10.79%; &lt; .0001). SUID rates were 2.68, 1.94, 1.46, 1.16, 0.73, and 0.51 per 1000 live births for 24 to 27, 28 to 31, 32 to 33, 34 to 36, 37 to 38, and 39 to 42 weeks' GA, respectively. Logistic regression models additionally indicated declines in the risk for SUID as GA increased. Prenatal smoking, inadequate prenatal care, and demographics associated with poverty were strongly associated with SUID. Despite the 2011 American Academy of Pediatrics recommendations for increased safe sleep education in the NICUs, SUID rates were inversely associated with GA in 2012 to 2013, suggesting that risk of SUID associated with prematurity has multiple etiologies requiring continued investigation, including biological vulnerabilities and the efficacy of NICU education programs, and that strategies to reduce SUID should be multifaceted.</abstract><cop>United States</cop><pub>American Academy of Pediatrics</pub><pmid>28759397</pmid><doi>10.1542/peds.2016-3334</doi><oa>free_for_read</oa></addata></record>
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subjects Analysis
Asphyxia
Autopsies
Cause of Death
Company business management
Complications and side effects
Death
Demographics
Demography
Economic conditions
Economic forecasts
Economic indicators
Female
Gestational Age
Humans
Infant
Infant Mortality
Infant, Newborn
Infant, Premature
Infants (Premature)
Logistic Models
Management
Patient outcomes
Pediatrics
Poverty
Practice guidelines (Medicine)
Premature infants
Prenatal care
Prenatal drug exposure
Regression analysis
Risk Factors
SIDS
Sleep
Smoking
Statistical data
Sudden Infant Death - epidemiology
Sudden Infant Death - etiology
Sudden infant death syndrome
United States
title Prematurity and Sudden Unexpected Infant Deaths in the United States
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