Down-regulated long non-coding RNA SNHG1 inhibits tumor genesis of colorectal carcinoma

BACKGROUND: Colorectal carcinoma (CRC) is the vital cancer mortality worldwide and the long noncoding RNAs (lncRNAs) is considered as an important biomarker. The aim of this study was to examine the influence of lncRNA-SNHG1in CRC, and explore the relationship of lncRNA-SNHG1 and CRC, and consequent...

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Veröffentlicht in:	Cancer biomarkers : section A of Disease markers 2017-07, Vol.20 (1), p.67-73
Hauptverfasser:	Sun, Xiantao, Wang, Zhimin, Yuan, Weitang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Animals Apoptosis Apoptosis - genetics Biomarkers Cancer Carcinogenesis Cell adhesion & migration Cell Line, Tumor Cell migration Cell Movement - genetics Cell Proliferation - genetics Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Colorectal Neoplasms - therapy Down-Regulation Female Gene expression Gene Expression Regulation, Neoplastic HCT116 Cells Humans Mice Middle Aged Non-coding RNA Patients Ribonucleic acid RNA RNA Interference RNA, Long Noncoding - genetics RNA-mediated interference RNAi Therapeutics - methods Tumor Burden - genetics Tumor cell lines Tumors Weight reduction Xenograft Model Antitumor Assays - methods
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