Emodin Induces Apoptosis of Colon Cancer Cells via Induction of Autophagy in a ROS-Dependent Manner

Recent studies revealed that emodin extracted from Chinese herbs exhibits an anticancer effect on different cancer types, including colon cancer. However, the mechanism is not well understood. In our study, we confirmed that emodin treatment inhibited cell viability and induced apoptosis in colon ca...

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Veröffentlicht in:	Oncology research 2018-07, Vol.26 (6), p.889-899
Hauptverfasser:	Wang, Yuanyuan, Luo, Qin, He, Xianlu, Wei, He, Wang, Ting, Shao, Jichun, Jiang, Xinni
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Apoptosis - drug effects Autophagy Colon Cancer Colonic Neoplasms - drug therapy Colonic Neoplasms - pathology Emodin Emodin - pharmacology Humans Protein Kinase Inhibitors - pharmacology Reactive Oxygen Species (ros) Reactive Oxygen Species - metabolism Tumor Cells, Cultured
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