Suppressive Effect of Ginsenoside Rg3 against Lipopolysaccharide-Induced Depression-Like Behavior and Neuroinflammation in Mice

Ginsenoside Rg3 (Rg3), a major active ingredient enriched in red ginseng, possesses well-confirmed immunoregulatory effects. Immune disturbance is a common trigger and aggravating factor of depression. The aim of this study was to explore the effects of Rg3 on lipopolysaccharide (LPS)-induced depres...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2017-08, Vol.65 (32), p.6861-6869
Hauptverfasser:	Kang, An, Xie, Tong, Zhu, Dong, Shan, Jinjun, Di, Liuqing, Zheng, Xiao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal Brain - drug effects Brain - immunology Depression - drug therapy Depression - genetics Depression - immunology Depression - psychology Ginsenosides - administration & dosage Ginsenosides - chemistry Humans Interleukin-6 - immunology Lipopolysaccharides - adverse effects Male Mice Mice, Inbred ICR Panax - chemistry Plant Extracts - administration & dosage Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - immunology
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