Evaluation of transporters in drug development: Current status and contemporary issues

Transporters govern the access of molecules to cells or their exit from cells, thereby controlling the overall distribution of drugs to their intracellular site of action. Clinically relevant drug-drug interactions mediated by transporters are of increasing interest in drug development. Drug transpo...

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Veröffentlicht in:Advanced drug delivery reviews 2017-07, Vol.116, p.100-118
Hauptverfasser: Lee, Sue-Chih, Arya, Vikram, Yang, Xinning, Volpe, Donna A., Zhang, Lei
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Sprache:eng
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