Antibodies against the mono-methylated arginine-glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 2 (EBNA2) identify potential cellular proteins targeted in viral transformation

The Epstein-Barr virus is a human herpes virus with oncogenic potential. The virus-encoded nuclear antigen 2 (EBNA2) is a key mediator of viral tumorigenesis. EBNA2 features an arginine-glycine (RG) repeat at amino acids (aa)339-354 that is essential for the transformation of lymphocytes and contain...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of general virology 2017-08, Vol.98 (8), p.2128-2142
Hauptverfasser:	Ayoubian, Hiresh, Fröhlich, Thomas, Pogodski, Dagmar, Flatley, Andrew, Kremmer, Elisabeth, Schepers, Aloys, Feederle, Regina, Arnold, Georg J, Grässer, Friedrich A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - metabolism Antibodies, Viral - metabolism Blotting, Western Cell Transformation, Viral Cross Reactions Epstein-Barr Virus Nuclear Antigens - metabolism Herpesvirus 4, Human - pathogenicity Host-Pathogen Interactions Humans Immunoprecipitation Mass Spectrometry Viral Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!