Amphotericin B Treatment for Indian Visceral Leishmaniasis: Conventional versus Lipid Formulations

In Bihar, India, where visceral leishmaniasis is hyperendemic, amphotericin B deoxycholate is now first-line parenteral treatment. To test the efficacy of amphotericin B deoxycholate versus that of its lipid formulations, Indian patients were randomized to receive treatment with amphotericin B deoxy...

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Veröffentlicht in:	Clinical infectious diseases 2004-02, Vol.38 (3), p.377-383
Hauptverfasser:	Sundar, Shyam, Mehta, Himanshu, Suresh, A. V., Singh, Shri P., Madhukar, Rai, Murray, Henry W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult amphotericin B Amphotericin B - adverse effects Amphotericin B - therapeutic use amphotericin B deoxycholate Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Antiprotozoal Agents - adverse effects Antiprotozoal Agents - therapeutic use Biological and medical sciences Child Child, Preschool Cost estimates Deoxycholic Acid - adverse effects Deoxycholic Acid - therapeutic use Diseases Dosage Drug Combinations Drug Costs Female Fever Hemoglobins Hospital Costs Human protozoal diseases Humans India - epidemiology Infant Infectious diseases Leishmania Leishmaniasis, Visceral - drug therapy Leishmaniasis, Visceral - epidemiology Leshmaniasis Lipids Liposomes Major Articles Male Medical cures Medical sciences Middle Aged Parasites Parasitic diseases Pharmacology. Drug treatments Phosphatidylcholines - adverse effects Phosphatidylcholines - therapeutic use Phosphatidylglycerols - adverse effects Phosphatidylglycerols - therapeutic use Protozoal diseases Treatment Outcome Visceral leishmaniasis
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