The enzyme-sensitive release of prodigiosin grafted β-cyclodextrin and chitosan magnetic nanoparticles as an anticancer drug delivery system: Synthesis, characterization and cytotoxicity studies

[Display omitted] •Polysaccharide coated nanocarriers were synthesized to design a drug release strategy.•Prodigiosin was chosen to survey its encapsulation on the synthesized nanocarriers.•Glycoside hydrolases were used to analysis the in vitro release of the drug.•PG-loaded nanocarriers showed sui...

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Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2017-10, Vol.158, p.589-601
Hauptverfasser:	Rastegari, Banafsheh, Karbalaei-Heidari, Hamid Reza, Zeinali, Sedigheh, Sheardown, Heather
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - chemistry beta-Cyclodextrins - chemistry Chitosan - chemistry Drug Delivery Systems - methods Lysosomal enzymes Lysosomes - chemistry Magnetite Nanoparticles - chemistry Microscopy, Electron, Transmission Polysaccharide coating Prodigiosin Prodigiosin - chemistry Selective delivery Spectroscopy, Fourier Transform Infrared X-Ray Diffraction
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