Towards an evidence based approach for the development of adjuvanted vaccines

•New adjuvants are typically a combination of delivery system and an immune potentiator.•A deeper understanding of innate immunity has helped the discovery of new adjuvants.•Adjuvant discovery and manufacture favor synthetic small molecule immune potentiators.•Aluminum salts (Alum) should remain the...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Current opinion in immunology 2017-08, Vol.47, p.93-102
Hauptverfasser:	O’Hagan, Derek T, Friedland, Leonard R, Hanon, Emmanuel, Didierlaurent, Arnaud M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive Immunity Adjuvants, Immunologic Animals Cytokines - metabolism Evidence-Based Medicine Female Hepatitis B - immunology Hepatitis B - prevention & control Humans Immunity, Innate Influenza Vaccines - immunology Malaria - immunology Mass Vaccination Uterine Cervical Neoplasms - immunology Vaccines - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!