Hepatoprotective effect of Opuntia microdasys (Lehm.) Pfeiff flowers against diabetes type II induced in rats

Opuntia sp. has long been used as a folk medicine to treat hepatitis and diabetes in Sicile (Italy). To extract the polyphenols from the flower of Opuntia microdasys Lehm. at post flowring stage and evaluate the antidiabetic activity in vitro and in vivo. The hepatoprotective activity of Opuntia mic...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2017-10, Vol.94, p.79-87
Hauptverfasser:	Chahdoura, Hassiba, Adouni, Khawla, Khlifi, Aida, Dridi, Ichrak, Haouas, Zohra, Neffati, Fadoua, Flamini, Guido, Mosbah, Habib, Achour, Lotfi
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Amylases - metabolism alpha-Glucosidases - metabolism Animals Antioxidants - metabolism Biomarkers - blood Diabetes Diabetes Mellitus, Experimental - blood Diabetes Mellitus, Experimental - drug therapy Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - drug therapy Flowers - chemistry Histopathology Inhibitory Concentration 50 Lipid Peroxidation - drug effects Liver - drug effects Liver - pathology Liver markers Male Metformin - pharmacology Metformin - therapeutic use Opuntia - chemistry Opuntia microdasys Lehm. flower Organ Size - drug effects Oxidative Stress - drug effects Plant Extracts - pharmacology Plant Extracts - therapeutic use Protective Agents - pharmacology Protective Agents - therapeutic use Protein Carbonylation - drug effects Rats, Wistar α-Amylase inhibition α-Glucosidase inhibition
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