Efficacy and Safety of MIN-101: A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial of a New Drug in Development for the Treatment of Negative Symptoms in Schizophrenia

Objective:The authors assessed the efficacy, safety, and tolerability of MIN-101, a compound with affinities for sigma-2 and 5-HT2A receptors and no direct dopamine affinities, in comparison with placebo in treating negative symptoms in stabilized patients with schizophrenia.Method:The trial enrolle...

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Veröffentlicht in:The American journal of psychiatry 2017-12, Vol.174 (12), p.1195-1202
Hauptverfasser: Davidson, Michael, Saoud, Jay, Staner, Corinne, Noel, Nadine, Luthringer, Elisabeth, Werner, Sandra, Reilly, Joseph, Schaffhauser, Jean-Yves, Rabinowitz, Jonathan, Weiser, Mark, Luthringer, Remy
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Sprache:eng
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