Inhibitory effects of Bombusae concretio Salicea on neuronal secretion of Alzheimer's β-amyloid peptides, a neurodegenerative peptide

Alzheimer's disease (AD) is characterized by the age-related deposition of beta-amyloid (A beta) 40/42 peptide aggregates in vulnerable brain regions. Multiple levels of evidence implicate a central role for A beta in the pathophysiology of AD. A beta is generated by the regulated cleavage of a...

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Veröffentlicht in:	Neurochemical research 2003-12, Vol.28 (12), p.1785-1792
Hauptverfasser:	JEONG, Ji-Cheon, KANG, Sung-Koo, YOON, Cheol-Ho, SEO, Young-Joon, HWANG, Cher-Won, KO, Jeong-Heon, LEE, Young-Choon, CHANG, Young-Chae, KIM, Cheorl-Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Alzheimer Disease - pathology Amyloid beta-Peptides - metabolism Animals Bambusae concretio Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Fundamental and applied biological sciences. Psychology Medical sciences Neurology Neurons - drug effects Neurons - metabolism Plant Extracts - pharmacology Salicaceae - chemistry Vertebrates: nervous system and sense organs
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