An evolutionary perspective on the systems of adaptive immunity

ABSTRACT We propose an evolutionary perspective to classify and characterize the diverse systems of adaptive immunity that have been discovered across all major domains of life. We put forward a new function‐based classification according to the way information is acquired by the immune systems: Dar...

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Veröffentlicht in:	Biological reviews of the Cambridge Philosophical Society 2018-02, Vol.93 (1), p.505-528
Hauptverfasser:	Müller, Viktor, de Boer, Rob J., Bonhoeffer, Sebastian, Szathmáry, Eörs
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive immunity Adaptive Immunity - genetics Adaptive systems Animals Antigens Biological Evolution Circuits Clonal selection Complexity Darwinian immunity Error feedback Evolution evolutionary scenario Feedback Genetic Fitness Immune response Immune system Immunity Information systems Innovations Lamarckian immunity major evolutionary transition Natural selection shotgun immunity Target acquisition Vertebrates Vertebrates - genetics Vertebrates - immunology
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