PTEN M-CBR3, a Versatile and Selective Regulator of Inositol 1,3,4,5,6- Pentakisphosphate (Ins(1,3,4,5,6)P sub(5)): Evidence for Ins(1,3,4,5,6)P sub(5) as a proliferative signal

The PTEN (phosphatase and tensin homologue deleted on chromosome 10) tumor suppressor is a phosphatidylinositol 3,4,5-trisphosphate (PtdInsP sub(3)) 3- phosphatase that plays a crucial role in regulating many cellular processes by antagonizing the phosphoinositide 3-kinase signaling pathway. Althoug...

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Veröffentlicht in:	The Journal of biological chemistry 2004-01, Vol.279 (2), p.1116-1122
Hauptverfasser:	Orchiston, E A, Bennett, D, Leslie, N R, Clarke, R G, Winward, L, Downes, C P, Safrany, ST
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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