Modulation of human Kv4.3/KChIP2 channel inactivation kinetics by cytoplasmic Ca2

The transient outward current ( I to ) in the human heart is mediated by Kv4.3 channels complexed with Kv channel interacting protein (KChIP) 2, a cytoplasmic Ca 2+ -binding EF-hand protein known to modulate Kv4.3 inactivation gating upon heterologous co-expression. We studied Kv4.3 channels co-expr...

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Veröffentlicht in:	Pflügers Archiv 2017-11, Vol.469 (11), p.1457-1470
Hauptverfasser:	Groen, Christiane, Bähring, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Cell Biology Human Physiology Ion channels Molecular Medicine Neurosciences Receptors Receptors and Transporters
Online-Zugang:	Volltext
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