Derisking Drug-Induced Carcinogenicity for Novel Therapeutics

Assessing the carcinogenic potential of innovative drugs spanning diverse therapeutic modalities and target biology represents a major challenge during drug development. Novel modalities, such as cell and gene therapies that involve intrinsic genetic modification of the host genome, require distinct...

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Veröffentlicht in:	Trends in Cancer 2016-08, Vol.2 (8), p.398-408
Hauptverfasser:	Moggs, Jonathan G, MacLachlan, Timothy, Martus, Hans-Joerg, Bentley, Philip
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carcinogenesis - chemically induced Carcinogens Drug Evaluation, Preclinical Drug-Related Side Effects and Adverse Reactions Humans Neoplasms - chemically induced Risk Assessment
Online-Zugang:	Volltext
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