Modifying the ICRP 66 dosimetry model based on results obtained from Mayak plutonium workers
Results obtained in a study of the microscopic distribution of plutonium in the lungs of deceased Pu workers from the Mayak Production Association showed that the long-term retention of Pu was greater than predicted by the current ICRP 66 respiratory tract dosimetry model (HRTM). These data were the...
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| Veröffentlicht in: | Radiation protection dosimetry 2003-01, Vol.105 (1-4), p.85-90 |
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| container_title | Radiation protection dosimetry |
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| creator | Romanov, S A Guilmette, R A Hahn, F F Nifatov, A P Zaytseva, Y V Lyovkina, Y V |
| description | Results obtained in a study of the microscopic distribution of plutonium in the lungs of deceased Pu workers from the Mayak Production Association showed that the long-term retention of Pu was greater than predicted by the current ICRP 66 respiratory tract dosimetry model (HRTM). These data were therefore applied to the HRTM by modifying selected parameters, namely the transfer rate of Pu from the transformed state compartment and the fraction of Pu that transfers to the bound state compartment. Invoking the latter compartment into the modelling allowed a better representation of the long-term Pu retention as well as providing a convenient means of describing the workplace-specific characteristics of the different Pu aerosols found in the Mayak plant. In particular, the present model describes a significantly greater long-term retention of Pu nitrate aerosols in the lung compared to the Type M default. |
| doi_str_mv | 10.1093/oxfordjournals.rpd.a006327 |
| format | Article |
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These data were therefore applied to the HRTM by modifying selected parameters, namely the transfer rate of Pu from the transformed state compartment and the fraction of Pu that transfers to the bound state compartment. Invoking the latter compartment into the modelling allowed a better representation of the long-term Pu retention as well as providing a convenient means of describing the workplace-specific characteristics of the different Pu aerosols found in the Mayak plant. In particular, the present model describes a significantly greater long-term retention of Pu nitrate aerosols in the lung compared to the Type M default.</description><identifier>ISSN: 0144-8420</identifier><identifier>EISSN: 1742-3406</identifier><identifier>DOI: 10.1093/oxfordjournals.rpd.a006327</identifier><identifier>PMID: 14526933</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Air Pollutants, Radioactive - analysis ; Air Pollutants, Radioactive - pharmacokinetics ; Body Burden ; Computer Simulation ; Female ; Humans ; Inhalation Exposure - analysis ; International Cooperation ; Lung - metabolism ; Lung - pathology ; Male ; Metabolic Clearance Rate - physiology ; Middle Aged ; Models, Biological ; Occupational Exposure - analysis ; Plutonium - analysis ; Plutonium - pharmacokinetics ; Power Plants ; Radiation Dosage ; Radiometry - methods ; Risk Assessment - methods ; Russia ; Societies ; Tissue Distribution</subject><ispartof>Radiation protection dosimetry, 2003-01, Vol.105 (1-4), p.85-90</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c384t-ef67ae68edf5af9ddbf5e76fbd14895b97e34353ec6107b204be103ea351f4753</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14526933$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Romanov, S A</creatorcontrib><creatorcontrib>Guilmette, R A</creatorcontrib><creatorcontrib>Hahn, F F</creatorcontrib><creatorcontrib>Nifatov, A P</creatorcontrib><creatorcontrib>Zaytseva, Y V</creatorcontrib><creatorcontrib>Lyovkina, Y V</creatorcontrib><title>Modifying the ICRP 66 dosimetry model based on results obtained from Mayak plutonium workers</title><title>Radiation protection dosimetry</title><addtitle>Radiat Prot Dosimetry</addtitle><description>Results obtained in a study of the microscopic distribution of plutonium in the lungs of deceased Pu workers from the Mayak Production Association showed that the long-term retention of Pu was greater than predicted by the current ICRP 66 respiratory tract dosimetry model (HRTM). These data were therefore applied to the HRTM by modifying selected parameters, namely the transfer rate of Pu from the transformed state compartment and the fraction of Pu that transfers to the bound state compartment. Invoking the latter compartment into the modelling allowed a better representation of the long-term Pu retention as well as providing a convenient means of describing the workplace-specific characteristics of the different Pu aerosols found in the Mayak plant. In particular, the present model describes a significantly greater long-term retention of Pu nitrate aerosols in the lung compared to the Type M default.</description><subject>Air Pollutants, Radioactive - analysis</subject><subject>Air Pollutants, Radioactive - pharmacokinetics</subject><subject>Body Burden</subject><subject>Computer Simulation</subject><subject>Female</subject><subject>Humans</subject><subject>Inhalation Exposure - analysis</subject><subject>International Cooperation</subject><subject>Lung - metabolism</subject><subject>Lung - pathology</subject><subject>Male</subject><subject>Metabolic Clearance Rate - physiology</subject><subject>Middle Aged</subject><subject>Models, Biological</subject><subject>Occupational Exposure - analysis</subject><subject>Plutonium - analysis</subject><subject>Plutonium - pharmacokinetics</subject><subject>Power Plants</subject><subject>Radiation Dosage</subject><subject>Radiometry - methods</subject><subject>Risk Assessment - methods</subject><subject>Russia</subject><subject>Societies</subject><subject>Tissue Distribution</subject><issn>0144-8420</issn><issn>1742-3406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkNtKAzEQhoMoWg-vIMEL77Ymm1PjndRDBUURFREhZJuJrt3d1GQX7du70qJ4NTDz_TPDh9ABJUNKNDsKXz5E9x662NgqDePcDS0hkuVqDQ2o4nnGOJHraEAo59mI52QLbaf0TkiutOCbaItykUvN2AC9XAdX-kXZvOL2DfDl-O4WS4ldSGUNbVzgOjiocGETOBwaHCF1VZtwKFpbNn3Px1Dja7uwMzyvujY0ZVfjzxBnENMu2vD9h7C3qjvo4fzsfjzJrm4uLscnV9mUjXibgZfKghyB88J67VzhBSjpC0f5SItCK2CcCQZTSYkqcsILoISBZYJ6rgTbQYfLvfMYPjpIranLNIWqsg2ELhmq81xSrnrweAlOY0gpgjfzWNY2Lgwl5set-e_W9G7Nym0f3l9d6Yoa3F90JbMHsiVQpha-fuc2zoxUTAkzeXo2k4vzU60fn8wd-wb4r4y9</recordid><startdate>20030101</startdate><enddate>20030101</enddate><creator>Romanov, S A</creator><creator>Guilmette, R A</creator><creator>Hahn, F F</creator><creator>Nifatov, A P</creator><creator>Zaytseva, Y V</creator><creator>Lyovkina, Y V</creator><general>Oxford University Press</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7TV</scope><scope>7U2</scope><scope>C1K</scope></search><sort><creationdate>20030101</creationdate><title>Modifying the ICRP 66 dosimetry model based on results obtained from Mayak plutonium workers</title><author>Romanov, S A ; Guilmette, R A ; Hahn, F F ; Nifatov, A P ; Zaytseva, Y V ; Lyovkina, Y V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c384t-ef67ae68edf5af9ddbf5e76fbd14895b97e34353ec6107b204be103ea351f4753</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Air Pollutants, Radioactive - analysis</topic><topic>Air Pollutants, Radioactive - pharmacokinetics</topic><topic>Body Burden</topic><topic>Computer Simulation</topic><topic>Female</topic><topic>Humans</topic><topic>Inhalation Exposure - analysis</topic><topic>International Cooperation</topic><topic>Lung - metabolism</topic><topic>Lung - pathology</topic><topic>Male</topic><topic>Metabolic Clearance Rate - physiology</topic><topic>Middle Aged</topic><topic>Models, Biological</topic><topic>Occupational Exposure - analysis</topic><topic>Plutonium - analysis</topic><topic>Plutonium - pharmacokinetics</topic><topic>Power Plants</topic><topic>Radiation Dosage</topic><topic>Radiometry - methods</topic><topic>Risk Assessment - methods</topic><topic>Russia</topic><topic>Societies</topic><topic>Tissue Distribution</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Romanov, S A</creatorcontrib><creatorcontrib>Guilmette, R A</creatorcontrib><creatorcontrib>Hahn, F F</creatorcontrib><creatorcontrib>Nifatov, A P</creatorcontrib><creatorcontrib>Zaytseva, Y V</creatorcontrib><creatorcontrib>Lyovkina, Y V</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Pollution Abstracts</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Radiation protection dosimetry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Romanov, S A</au><au>Guilmette, R A</au><au>Hahn, F F</au><au>Nifatov, A P</au><au>Zaytseva, Y V</au><au>Lyovkina, Y V</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Modifying the ICRP 66 dosimetry model based on results obtained from Mayak plutonium workers</atitle><jtitle>Radiation protection dosimetry</jtitle><addtitle>Radiat Prot Dosimetry</addtitle><date>2003-01-01</date><risdate>2003</risdate><volume>105</volume><issue>1-4</issue><spage>85</spage><epage>90</epage><pages>85-90</pages><issn>0144-8420</issn><eissn>1742-3406</eissn><abstract>Results obtained in a study of the microscopic distribution of plutonium in the lungs of deceased Pu workers from the Mayak Production Association showed that the long-term retention of Pu was greater than predicted by the current ICRP 66 respiratory tract dosimetry model (HRTM). These data were therefore applied to the HRTM by modifying selected parameters, namely the transfer rate of Pu from the transformed state compartment and the fraction of Pu that transfers to the bound state compartment. Invoking the latter compartment into the modelling allowed a better representation of the long-term Pu retention as well as providing a convenient means of describing the workplace-specific characteristics of the different Pu aerosols found in the Mayak plant. In particular, the present model describes a significantly greater long-term retention of Pu nitrate aerosols in the lung compared to the Type M default.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>14526933</pmid><doi>10.1093/oxfordjournals.rpd.a006327</doi><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 0144-8420 |
| ispartof | Radiation protection dosimetry, 2003-01, Vol.105 (1-4), p.85-90 |
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| language | eng |
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| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current) |
| subjects | Air Pollutants, Radioactive - analysis Air Pollutants, Radioactive - pharmacokinetics Body Burden Computer Simulation Female Humans Inhalation Exposure - analysis International Cooperation Lung - metabolism Lung - pathology Male Metabolic Clearance Rate - physiology Middle Aged Models, Biological Occupational Exposure - analysis Plutonium - analysis Plutonium - pharmacokinetics Power Plants Radiation Dosage Radiometry - methods Risk Assessment - methods Russia Societies Tissue Distribution |
| title | Modifying the ICRP 66 dosimetry model based on results obtained from Mayak plutonium workers |
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