Interleukin 1 Activates STAT3/Nuclear Factor-κB Cross-talk via a Unique TRAF6- and p65-dependent Mechanism

Interleukins (IL) 1 and 6 are important cytokines that function via the activation, respectively, of the transcription factors NF-κB and STAT3. We have observed that a specific type of κB DNA sequence motif supports both NF-κB p65 homodimer binding and cooperativity with non-tyrosine-phosphorylated...

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Veröffentlicht in:	The Journal of biological chemistry 2004-01, Vol.279 (3), p.1768-1776
Hauptverfasser:	Yoshida, Yasuhiro, Kumar, Arvind, Koyama, Yoshinobu, Peng, Haibing, Arman, Ahmet, Boch, Jason A., Auron, Philip E.
Format:	Artikel
Sprache:	eng
Schlagworte:	NF-^KB protein STAT3 protein TRAF6 protein
Online-Zugang:	Volltext
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