Use of a vaccine strain of measles virus genetically engineered to produce carcinoembryonic antigen as a novel therapeutic agent against glioblastoma multiforme

Despite the most aggressive medical and surgical treatments, glioblastoma multiforme remains incurable with a median survival of

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Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2003-05, Vol.63 (10), p.2462-2469
Hauptverfasser:	PHUONG, Loi K, ALLEN, Cory, PENG, Kah-Whye, GIANNINI, Caterina, GREINER, Suzanne, TENEYCK, Cynthia J, MISHRA, Prasanna K, MACURA, Slobodan I, RUSSELL, Stephen J, GALANIS, Evanthia C
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Antigens, CD - biosynthesis Antigens, CD - genetics Antigens, CD - immunology Apoptosis - physiology Applied cell therapy and gene therapy Biological and medical sciences Brain Neoplasms - genetics Brain Neoplasms - immunology Brain Neoplasms - therapy Cancer Vaccines - adverse effects Cancer Vaccines - genetics Cancer Vaccines - immunology Cancer Vaccines - pharmacology Carcinoembryonic Antigen - biosynthesis Carcinoembryonic Antigen - blood Carcinoembryonic Antigen - genetics Carcinoembryonic Antigen - immunology Cercopithecus aethiops Genetic Engineering - methods Glioblastoma - genetics Glioblastoma - immunology Glioblastoma - therapy Humans Measles Vaccine - adverse effects Measles Vaccine - genetics Measles Vaccine - immunology Measles Vaccine - pharmacology Measles virus Measles virus - genetics Measles virus - immunology Medical sciences Membrane Cofactor Protein Membrane Glycoproteins - biosynthesis Membrane Glycoproteins - genetics Membrane Glycoproteins - immunology Mice Mice, Inbred BALB C Mice, Nude Mice, Transgenic Transfusions. Complications. Transfusion reactions. Cell and gene therapy Tumor Cells, Cultured Vero Cells Xenograft Model Antitumor Assays
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Beschreibung
Zusammenfassung:	Despite the most aggressive medical and surgical treatments, glioblastoma multiforme remains incurable with a median survival of
ISSN:	0008-5472 1538-7445