The Triple Roles of Glutathione for a DNA-Cleaving DNAzyme and Development of a Fluorescent Glutathione/Cu2+-Dependent DNAzyme Sensor for Detection of Cu2+ in Drinking Water

Pistol-like DNAzyme (PLDz) is an oxidative DNA-cleaving catalytic DNA with ascorbic acid as cofactor. Herein, glutathione was induced into the reaction system to maintain reduced ascorbic acid levels for higher efficient cleavage. However, data indicated that glutathione played triple roles in PLDz-...

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Veröffentlicht in:	ACS sensors 2017-03, Vol.2 (3), p.364-370
Hauptverfasser:	Wang, Shijin, Liu, Chengcheng, Li, Guiying, Sheng, Yongjie, Sun, Yanhong, Rui, Hongyue, Zhang, Jin, Xu, Jiacui, Jiang, Dazhi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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