Sesamin prevents apoptosis and inflammation after experimental myocardial infarction by JNK and NF-κB pathways

Myocardial infarction is a devastating event, especially when reperfusion is not performed. The inflammatory response has been associated with the pathogenesis of left ventricular remodeling after myocardial infarction. This study focused on the anti-apoptotic and anti-inflammatory effects of sesami...

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Veröffentlicht in:	Food & function 2017-08, Vol.8 (8), p.2875-2885
Hauptverfasser:	Fan, Di, Yang, Zheng, Yuan, Yuan, Wu, Qing-Qing, Xu, Man, Jin, Ya-Ge, Tang, Qi-Zhu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects bcl-2-Associated X Protein - genetics bcl-2-Associated X Protein - immunology Dioxoles - administration & dosage Disease Models, Animal Humans Lignans - administration & dosage Male MAP Kinase Kinase 4 - genetics MAP Kinase Kinase 4 - immunology Mice Myocardial Infarction - drug therapy Myocardial Infarction - genetics Myocardial Infarction - immunology Myocardial Infarction - physiopathology NF-kappa B - genetics NF-kappa B - immunology Plant Extracts - administration & dosage Sesamum - chemistry Signal Transduction - drug effects
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