Characterization of a presymptomatic stage in a Drosophila Parkinson's disease model: Unveiling dopaminergic compensatory mechanisms

Parkinson's disease (PD) is a degenerative disorder characterized by several motor symptoms including shaking, rigidity, slow movement and difficult walking, which has been associated to the death of nigro-striatal dopaminergic neurons. >90% of PD patients also present olfactory dysfunction....

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular basis of disease 2017-11, Vol.1863 (11), p.2882-2890
Hauptverfasser:	Molina-Mateo, Daniela, Fuenzalida-Uribe, Nicolás, Hidalgo, Sergio, Molina-Fernández, Claudia, Abarca, Jorge, Zárate, Rafaella V., Escandón, Marcela, Figueroa, Reinaldo, Tevy, María Florencia, Campusano, Jorge M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosynthetic enzymes Dopamine transporter Dopaminergic neurons Drosophila Parkinson's disease
Online-Zugang:	Volltext
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