Comparison of oxidative stress and changes of xenobiotic metabolizing enzymes induced by phthalates in rats

Phthalates are widely used as a plasticizer and cause a peroxisome proliferation. Peroxisome proliferators (PPs), such as di-2-ethylhexyl phthalate (DEHP) and clofibrate (CF) are known to have a hepatocarcinogenic potential in rodents. It has been proposed that these PPs may cause hepatocellular can...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Food and chemical toxicology 2004, Vol.42 (1), p.107-114
Hauptverfasser:	Seo, K.W, Kim, K.B, Kim ,Y.J, Choi, J.Y, Lee, K.T, Choi, K.S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences cell proliferation Chemical and industrial products toxicology. Toxic occupational diseases Clofibrate - pharmacology Cytosol - drug effects Cytosol - enzymology DNA - chemistry DNA - isolation & purification DNA - metabolism enzymes Hypolipidemic Agents - pharmacology Liver - chemistry Liver - enzymology Liver - metabolism Male Malondialdehyde - metabolism Medical sciences metabolism Microsomes, Liver - drug effects Microsomes, Liver - enzymology Organ Size - drug effects oxidative stress Oxidative Stress - drug effects packaging materials Peroxisome Proliferators - metabolism peroxisomes phthalates Phthalic Acids - toxicity plasticizers Rats Rats, Sprague-Dawley Toxicology Various organic compounds xenobiotic metabolizing enzymes xenobiotics Xenobiotics - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!