The lncRNA NEAT1 facilitates cell growth and invasion via the miR-211/HMGA2 axis in breast cancer

Long non-coding RNAs play a significant role in cancer metastasis. Studies have demonstrated that LncRNA NEAT1 promotes cancer progression. We aimed to explore whether NEAT1 regulated growth and invasion in breast cancer cells. We provided evidence that lncRNA NEAT1 was up-regulated in breast cancer...

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Veröffentlicht in:	International journal of biological macromolecules 2017-12, Vol.105 (Pt 1), p.346-353
Hauptverfasser:	Li, Xuerui, Wang, Shuxia, Li, Zhenzhong, Long, Xiaoyu, Guo, Zibai, Zhang, Guochun, Zu, Jian, Chen, Yu, Wen, Linzhu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Breast Neoplasms - diagnosis Breast Neoplasms - genetics Breast Neoplasms - pathology Cell Line, Tumor Cell Proliferation - genetics Epithelial-Mesenchymal Transition - genetics Female Gene Expression Regulation, Neoplastic HMGA2 HMGA2 Protein - metabolism Humans Mice MicroRNAs - genetics Middle Aged miR-211 NEAT1 Neoplasm Invasiveness Neoplasm Metastasis Phenotype Prognosis RNA, Long Noncoding - genetics Up-Regulation
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