Advanced methodologies for cocrystal synthesis

Pharmaceutical cocrystals are multicomponent systems composed of two or more molecules and held together by H-bonding. Currently, cocrystals provide exciting opportunities in the pharmaceutical industry for the development and manufacturing of new medicines by improving poor physical properties of A...

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Veröffentlicht in:	Advanced drug delivery reviews 2017-08, Vol.117, p.178-195
Hauptverfasser:	Douroumis, Dennis, Ross, Steven A., Nokhodchi, Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Antisolvent Chemistry, Pharmaceutical - methods Cocrystals Continuous Crystallization Freeze – drying Hot melt extrusion Mechanochemical grinding Microfluidics Pharmaceutical Preparations - chemistry Scale-up Spray – drying Ultrasound
Online-Zugang:	Volltext
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