The BRAF and NRAS mutation prevalence in dermoscopic subtypes of acquired naevi reveals constitutive mitogen‐activated protein kinase pathway activation

Summary Background Acquired naevi can have unique dermoscopic patterns that correspond to distinct microanatomical growth patterns. Previous studies on acquired naevi stratified according to dermoscopic pattern focused on the frequency of somatic BRAF mutations, whereas NRAS mutations remained to be...

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Veröffentlicht in:	British journal of dermatology (1951) 2018-01, Vol.178 (1), p.191-197
Hauptverfasser:	Tan, J.M., Tom, L.N., Jagirdar, K., Lambie, D., Schaider, H., Sturm, R.A., Soyer, H.P., Stark, M.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Benign Growth patterns Kinases Life cycles MAP kinase Melanoma Mutation Polymerase chain reaction Protein kinase Proteins Risk assessment
Online-Zugang:	Volltext
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