Dynamic Organization of Chromatin Domains Revealed by Super-Resolution Live-Cell Imaging

The eukaryotic genome is organized within cells as chromatin. For proper information output, higher-order chromatin structures can be regulated dynamically. How such structures form and behave in various cellular processes remains unclear. Here, by combining super-resolution imaging (photoactivated...

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Veröffentlicht in:	Molecular cell 2017-07, Vol.67 (2), p.282-293.e7
Hauptverfasser:	Nozaki, Tadasu, Imai, Ryosuke, Tanbo, Mai, Nagashima, Ryosuke, Tamura, Sachiko, Tani, Tomomi, Joti, Yasumasa, Tomita, Masaru, Hibino, Kayo, Kanemaki, Masato T., Wendt, Kerstin S., Okada, Yasushi, Nagai, Takeharu, Maeshima, Kazuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Cycle Proteins - metabolism Cell Differentiation chromatin Chromatin Assembly and Disassembly chromatin domain chromatin dynamics Chromosomal Proteins, Non-Histone - metabolism chromosome Chromosomes, Human Cohesins HCT116 Cells HeLa Cells Heterochromatin - chemistry Heterochromatin - metabolism Humans Mice Microscopy, Video - methods Mitosis Motion Nucleic Acid Conformation Nucleosomes - chemistry Nucleosomes - metabolism PALM Protein Conformation RNA Interference single-nucleosome tracking Structure-Activity Relationship Time Factors Transcription, Genetic Transfection
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