Overexpression of Derlin 3 is associated with malignant phenotype of breast cancer cells

Breast cancer (BC) is the most common malignant tumor among women worldwide. Development of novel molecular targets is important to improve prognosis of BC patients. Derlin 3 (DERL3) gene is a member of derlin family, and its coding protein is critical to the endoplasmic reticulum-associated degrada...

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Veröffentlicht in:	Oncology reports 2017-09, Vol.38 (3), p.1760-1766
Hauptverfasser:	Shibata, Masahiro, Kanda, Mitsuro, Tanaka, Haruyoshi, Umeda, Shinichi, Miwa, Takashi, Shimizu, Dai, Hayashi, Masamichi, Inaishi, Takahiro, Miyajima, Noriyuki, Adachi, Yayoi, Takano, Yuko, Nakanishi, Kenichi, Takeuchi, Dai, Noda, Sumiyo, Kodera, Yasuhiro, Kikumori, Toyone
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antibiotics biomarker Biomarkers, Tumor - genetics Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Care and treatment Cell Line, Tumor Cell Proliferation - genetics Chemotherapy DERL3 Development and progression Endocrine therapy Endoplasmic reticulum Endoplasmic Reticulum-Associated Degradation - genetics Epidermal growth factor expression Female Gene expression Gene Expression Regulation, Neoplastic - genetics Genetic aspects Health aspects Humans Lymphatic Metastasis - genetics Lymphatic Metastasis - pathology MCF-7 Cells Medical prognosis Membrane Proteins - genetics Middle Aged Multivariate analysis Oncogenes Patients Phenotype Phenotypes Prognosis progression Proteins RNA, Messenger - genetics Studies
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