The effects of Escherichia coli capsule, O-antigen, host neutrophils, and complement in a rat model of Gram-negative pneumonia

Gram-negative enteric bacilli are agents of life-threatening pneumonia. The role of the bacterial capsule and O-antigen moiety of lipopolysaccharide in the pathogenesis of Gram-negative pneumonia was assessed. In a rat model of pneumonia the LD 50 of a wild-type extraintestinal pathogenic Escherichi...

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Veröffentlicht in:FEMS microbiology letters 2003-09, Vol.226 (2), p.355-361
Hauptverfasser: Russo, Thomas A, Davidson, Bruce A, Carlino-MacDonald, Ulrike B, Helinski, Jadwiga D, Priore, Roger L, Knight, Paul R
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Sprache:eng
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