Bone mineral density measurements in otosclerosis using dual-energy X-ray absorptiometry
Objectives This study aims to evaluate patients with otosclerosis with respect to bone mineral density (BMD) at different regions of interest (ROI), using dual‐energy X‐ray absorptiometry (DXA). Design Cross‐sectional controlled study. Setting Tertiary referral hospital. Participants The patients wi...
Gespeichert in:
| Veröffentlicht in: | Clinical otolaryngology 2016-04, Vol.41 (2), p.149-153 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 153 |
|---|---|
| container_issue | 2 |
| container_start_page | 149 |
| container_title | Clinical otolaryngology |
| container_volume | 41 |
| creator | Tonuk, S.B. Koybasi, S. Bicer, Y.O. Alkan Temel, S. |
| description | Objectives
This study aims to evaluate patients with otosclerosis with respect to bone mineral density (BMD) at different regions of interest (ROI), using dual‐energy X‐ray absorptiometry (DXA).
Design
Cross‐sectional controlled study.
Setting
Tertiary referral hospital.
Participants
The patients with a definite diagnosis of otosclerosis confirmed intra‐operatively were defined as the study group (n = 30). The control group consisted of volunteer, healthy subjects with normal hearing (n = 43).
Main outcome measures
Following an audiometric evaluation, a venous blood sample was obtained and a single BMD measurement using DXA was applied to each participant.
Results
The mean BMD, T and Z scores were higher in the otosclerosis group than in the control group in all the regions considered, but not significantly; only the L2‐L3 lateral BMD and its T and Z scores were significant (P = 0.036, P = 0.029 and P = 0.036, respectively).
Conclusion
This study shows that the BMD does not decrease in the presence of otosclerosis despite its genetic and metabolic relevance with osteoporosis. Concerning the L2‐L3 lateral BMD measurements, the BMD increased in otosclerosis. |
| doi_str_mv | 10.1111/coa.12486 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1919973860</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1919973860</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4246-780cbeaec6dd869b577b15c5434b6987ceb5737349b41457d23a74a40376253a3</originalsourceid><addsrcrecordid>eNqFkU9P3DAQxS1UVCj00C9QWeqlHAL-Fzs-wqpsEajbAwjExXKcAZkm8WIngnz7uuyyB6SKuczI_r0nzTyEvlBySHMduWAPKROV3EK7VAldiDx_2Myq2kGfUnogRHCi6Ee0wyTRMv_uopuT0APufA_RtriBPvlhwh3YNEbooB8S9j0OQ0iuhRiST3hMvr_HzWjbArLsfsI3RbQTtnUKcTn40MEQp320fWfbBJ_XfQ9dnf64nP0sLhbzs9nxReEEE7JQFXE1WHCyaSqp61KpmpauFFzUUlfKQX7iigtdCypK1TBulbCCcCVZyS3fQ99XvssYHkdIg-l8ctC2tocwJkM11VrxSpL3UaUIY1RzltFvb9CHMMY-L5IpqZkUtNSZOlhRLl8mRbgzy-g7GydDifmXjMnJmJdkMvt17TjWHTQb8jWKDBytgCffwvR_JzNbHL9aFiuFTwM8bxQ2_jEy36w017_mpjqfn9wS_dsQ_hfVw6WP</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1769264159</pqid></control><display><type>article</type><title>Bone mineral density measurements in otosclerosis using dual-energy X-ray absorptiometry</title><source>MEDLINE</source><source>Wiley Online Library All Journals</source><creator>Tonuk, S.B. ; Koybasi, S. ; Bicer, Y.O. ; Alkan Temel, S.</creator><creatorcontrib>Tonuk, S.B. ; Koybasi, S. ; Bicer, Y.O. ; Alkan Temel, S.</creatorcontrib><description>Objectives
This study aims to evaluate patients with otosclerosis with respect to bone mineral density (BMD) at different regions of interest (ROI), using dual‐energy X‐ray absorptiometry (DXA).
Design
Cross‐sectional controlled study.
Setting
Tertiary referral hospital.
Participants
The patients with a definite diagnosis of otosclerosis confirmed intra‐operatively were defined as the study group (n = 30). The control group consisted of volunteer, healthy subjects with normal hearing (n = 43).
Main outcome measures
Following an audiometric evaluation, a venous blood sample was obtained and a single BMD measurement using DXA was applied to each participant.
Results
The mean BMD, T and Z scores were higher in the otosclerosis group than in the control group in all the regions considered, but not significantly; only the L2‐L3 lateral BMD and its T and Z scores were significant (P = 0.036, P = 0.029 and P = 0.036, respectively).
Conclusion
This study shows that the BMD does not decrease in the presence of otosclerosis despite its genetic and metabolic relevance with osteoporosis. Concerning the L2‐L3 lateral BMD measurements, the BMD increased in otosclerosis.</description><identifier>ISSN: 1749-4478</identifier><identifier>EISSN: 1749-4486</identifier><identifier>DOI: 10.1111/coa.12486</identifier><identifier>PMID: 26096174</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Absorptiometry, Photon ; Adult ; Audiometry ; Bone Density ; Case-Control Studies ; Cross-Sectional Studies ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Luminescence ; Male ; Otosclerosis - blood ; Otosclerosis - diagnostic imaging ; Parathyroid Hormone - blood ; Vitamin D - blood</subject><ispartof>Clinical otolaryngology, 2016-04, Vol.41 (2), p.149-153</ispartof><rights>2015 John Wiley & Sons Ltd</rights><rights>2015 John Wiley & Sons Ltd.</rights><rights>2016 John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4246-780cbeaec6dd869b577b15c5434b6987ceb5737349b41457d23a74a40376253a3</citedby><cites>FETCH-LOGICAL-c4246-780cbeaec6dd869b577b15c5434b6987ceb5737349b41457d23a74a40376253a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fcoa.12486$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fcoa.12486$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26096174$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tonuk, S.B.</creatorcontrib><creatorcontrib>Koybasi, S.</creatorcontrib><creatorcontrib>Bicer, Y.O.</creatorcontrib><creatorcontrib>Alkan Temel, S.</creatorcontrib><title>Bone mineral density measurements in otosclerosis using dual-energy X-ray absorptiometry</title><title>Clinical otolaryngology</title><addtitle>Clin Otolaryngol</addtitle><description>Objectives
This study aims to evaluate patients with otosclerosis with respect to bone mineral density (BMD) at different regions of interest (ROI), using dual‐energy X‐ray absorptiometry (DXA).
Design
Cross‐sectional controlled study.
Setting
Tertiary referral hospital.
Participants
The patients with a definite diagnosis of otosclerosis confirmed intra‐operatively were defined as the study group (n = 30). The control group consisted of volunteer, healthy subjects with normal hearing (n = 43).
Main outcome measures
Following an audiometric evaluation, a venous blood sample was obtained and a single BMD measurement using DXA was applied to each participant.
Results
The mean BMD, T and Z scores were higher in the otosclerosis group than in the control group in all the regions considered, but not significantly; only the L2‐L3 lateral BMD and its T and Z scores were significant (P = 0.036, P = 0.029 and P = 0.036, respectively).
Conclusion
This study shows that the BMD does not decrease in the presence of otosclerosis despite its genetic and metabolic relevance with osteoporosis. Concerning the L2‐L3 lateral BMD measurements, the BMD increased in otosclerosis.</description><subject>Absorptiometry, Photon</subject><subject>Adult</subject><subject>Audiometry</subject><subject>Bone Density</subject><subject>Case-Control Studies</subject><subject>Cross-Sectional Studies</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Female</subject><subject>Humans</subject><subject>Luminescence</subject><subject>Male</subject><subject>Otosclerosis - blood</subject><subject>Otosclerosis - diagnostic imaging</subject><subject>Parathyroid Hormone - blood</subject><subject>Vitamin D - blood</subject><issn>1749-4478</issn><issn>1749-4486</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU9P3DAQxS1UVCj00C9QWeqlHAL-Fzs-wqpsEajbAwjExXKcAZkm8WIngnz7uuyyB6SKuczI_r0nzTyEvlBySHMduWAPKROV3EK7VAldiDx_2Myq2kGfUnogRHCi6Ee0wyTRMv_uopuT0APufA_RtriBPvlhwh3YNEbooB8S9j0OQ0iuhRiST3hMvr_HzWjbArLsfsI3RbQTtnUKcTn40MEQp320fWfbBJ_XfQ9dnf64nP0sLhbzs9nxReEEE7JQFXE1WHCyaSqp61KpmpauFFzUUlfKQX7iigtdCypK1TBulbCCcCVZyS3fQ99XvssYHkdIg-l8ctC2tocwJkM11VrxSpL3UaUIY1RzltFvb9CHMMY-L5IpqZkUtNSZOlhRLl8mRbgzy-g7GydDifmXjMnJmJdkMvt17TjWHTQb8jWKDBytgCffwvR_JzNbHL9aFiuFTwM8bxQ2_jEy36w017_mpjqfn9wS_dsQ_hfVw6WP</recordid><startdate>201604</startdate><enddate>201604</enddate><creator>Tonuk, S.B.</creator><creator>Koybasi, S.</creator><creator>Bicer, Y.O.</creator><creator>Alkan Temel, S.</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope><scope>7QP</scope></search><sort><creationdate>201604</creationdate><title>Bone mineral density measurements in otosclerosis using dual-energy X-ray absorptiometry</title><author>Tonuk, S.B. ; Koybasi, S. ; Bicer, Y.O. ; Alkan Temel, S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4246-780cbeaec6dd869b577b15c5434b6987ceb5737349b41457d23a74a40376253a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Absorptiometry, Photon</topic><topic>Adult</topic><topic>Audiometry</topic><topic>Bone Density</topic><topic>Case-Control Studies</topic><topic>Cross-Sectional Studies</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>Female</topic><topic>Humans</topic><topic>Luminescence</topic><topic>Male</topic><topic>Otosclerosis - blood</topic><topic>Otosclerosis - diagnostic imaging</topic><topic>Parathyroid Hormone - blood</topic><topic>Vitamin D - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tonuk, S.B.</creatorcontrib><creatorcontrib>Koybasi, S.</creatorcontrib><creatorcontrib>Bicer, Y.O.</creatorcontrib><creatorcontrib>Alkan Temel, S.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Calcium & Calcified Tissue Abstracts</collection><jtitle>Clinical otolaryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tonuk, S.B.</au><au>Koybasi, S.</au><au>Bicer, Y.O.</au><au>Alkan Temel, S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bone mineral density measurements in otosclerosis using dual-energy X-ray absorptiometry</atitle><jtitle>Clinical otolaryngology</jtitle><addtitle>Clin Otolaryngol</addtitle><date>2016-04</date><risdate>2016</risdate><volume>41</volume><issue>2</issue><spage>149</spage><epage>153</epage><pages>149-153</pages><issn>1749-4478</issn><eissn>1749-4486</eissn><abstract>Objectives
This study aims to evaluate patients with otosclerosis with respect to bone mineral density (BMD) at different regions of interest (ROI), using dual‐energy X‐ray absorptiometry (DXA).
Design
Cross‐sectional controlled study.
Setting
Tertiary referral hospital.
Participants
The patients with a definite diagnosis of otosclerosis confirmed intra‐operatively were defined as the study group (n = 30). The control group consisted of volunteer, healthy subjects with normal hearing (n = 43).
Main outcome measures
Following an audiometric evaluation, a venous blood sample was obtained and a single BMD measurement using DXA was applied to each participant.
Results
The mean BMD, T and Z scores were higher in the otosclerosis group than in the control group in all the regions considered, but not significantly; only the L2‐L3 lateral BMD and its T and Z scores were significant (P = 0.036, P = 0.029 and P = 0.036, respectively).
Conclusion
This study shows that the BMD does not decrease in the presence of otosclerosis despite its genetic and metabolic relevance with osteoporosis. Concerning the L2‐L3 lateral BMD measurements, the BMD increased in otosclerosis.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>26096174</pmid><doi>10.1111/coa.12486</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1749-4478 |
| ispartof | Clinical otolaryngology, 2016-04, Vol.41 (2), p.149-153 |
| issn | 1749-4478 1749-4486 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1919973860 |
| source | MEDLINE; Wiley Online Library All Journals |
| subjects | Absorptiometry, Photon Adult Audiometry Bone Density Case-Control Studies Cross-Sectional Studies Enzyme-Linked Immunosorbent Assay Female Humans Luminescence Male Otosclerosis - blood Otosclerosis - diagnostic imaging Parathyroid Hormone - blood Vitamin D - blood |
| title | Bone mineral density measurements in otosclerosis using dual-energy X-ray absorptiometry |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T21%3A53%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Bone%20mineral%20density%20measurements%20in%20otosclerosis%20using%20dual-energy%20X-ray%20absorptiometry&rft.jtitle=Clinical%20otolaryngology&rft.au=Tonuk,%20S.B.&rft.date=2016-04&rft.volume=41&rft.issue=2&rft.spage=149&rft.epage=153&rft.pages=149-153&rft.issn=1749-4478&rft.eissn=1749-4486&rft_id=info:doi/10.1111/coa.12486&rft_dat=%3Cproquest_cross%3E1919973860%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1769264159&rft_id=info:pmid/26096174&rfr_iscdi=true |