Sageretia thea (Osbeck.) mediated synthesis of zinc oxide nanoparticles and its biological applications
To investigate the physical and biological properties of bioinspired zinc oxide (ZnO) nanoparticles via aqueous leaf extracts of Sageretia thea. Nanoparticles of size approximately 12.4 nm were extensively characterized. In vitro antimicrobial, cytotoxic, biocompatible and enzyme inhibition assays w...
Gespeichert in:
| Veröffentlicht in: | Nanomedicine (London, England) England), 2017-08, Vol.12 (15), p.1767-1789 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1789 |
|---|---|
| container_issue | 15 |
| container_start_page | 1767 |
| container_title | Nanomedicine (London, England) |
| container_volume | 12 |
| creator | Khalil, Ali Talha Ovais, Muhammad Ullah, Ikram Ali, Muhammad Shinwari, Zabta Khan Khamlich, Saleh Maaza, Malik |
| description | To investigate the physical and biological properties of bioinspired zinc oxide (ZnO) nanoparticles via aqueous leaf extracts of Sageretia thea.
Nanoparticles of size approximately 12.4 nm were extensively characterized. In vitro antimicrobial, cytotoxic, biocompatible and enzyme inhibition assays were performed.
Significant antimicrobial activities with and without UV illumination are reported. Bioinspired ZnO nanoparticles were found effective against fungal strains. MTT assay was performed to check the leishmanicidal activity against promastigotes (IC
: 6.2 μg/ml) and amastigotes (IC
: 10.87 μg/ml) of Leishmania tropica. Brine shrimp lethality was also indicated by bioinspired ZnO nanoparticles (IC
: 21.29 μg/ml).
Hemocompatible nature of bioinspired nanoparticles was revealed. Furthermore, the antioxidant activities were performed. In addition, significant protein kinase while insignificant alpha amylase inhibition were recorded. |
| doi_str_mv | 10.2217/nnm-2017-0124 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1918383144</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1918383144</sourcerecordid><originalsourceid>FETCH-LOGICAL-c321t-4baa4080945aa059a82099cbd91221cf6b57792537581b27a617230928b1f863</originalsourceid><addsrcrecordid>eNpdkUtPwzAQhC0EolA4ckWWuJRDih952EdU8ZIq9UDv1sZxiktqhziVKL8ehxYOnHak_TTanUHoipIpY7S4c26TMEKLhFCWHqEzWqQiyWXOj380TzIh5Aidh7AmJBOMklM0YiKXUnBxhlavsDKd6S3g_s0AnixCafT79BZvTGWhNxUOOxdXwQbsa_xlncb-01YGO3C-ha63ujEBg6uw7QMurW_8ympoMLRtE0VvvQsX6KSGJpjLwxyj5ePDcvaczBdPL7P7eaI5o32SlgApEUSmGQDJJAhGpNRlJWn8Vtd5mRWFZBkvMkFLVkBOC8aJZKKktcj5GE32tm3nP7Ym9GpjgzZNA874bVBU0vg2p2ka0Zt_6NpvOxePUyzekosIDVSyp3TnQ-hMrdrObqDbKUrUUICKBaihADUUEPnrg-u2jAn-0b-J82_XnH_s</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2321681444</pqid></control><display><type>article</type><title>Sageretia thea (Osbeck.) mediated synthesis of zinc oxide nanoparticles and its biological applications</title><source>PubMed (Medline)</source><source>MEDLINE</source><creator>Khalil, Ali Talha ; Ovais, Muhammad ; Ullah, Ikram ; Ali, Muhammad ; Shinwari, Zabta Khan ; Khamlich, Saleh ; Maaza, Malik</creator><creatorcontrib>Khalil, Ali Talha ; Ovais, Muhammad ; Ullah, Ikram ; Ali, Muhammad ; Shinwari, Zabta Khan ; Khamlich, Saleh ; Maaza, Malik</creatorcontrib><description>To investigate the physical and biological properties of bioinspired zinc oxide (ZnO) nanoparticles via aqueous leaf extracts of Sageretia thea.
Nanoparticles of size approximately 12.4 nm were extensively characterized. In vitro antimicrobial, cytotoxic, biocompatible and enzyme inhibition assays were performed.
Significant antimicrobial activities with and without UV illumination are reported. Bioinspired ZnO nanoparticles were found effective against fungal strains. MTT assay was performed to check the leishmanicidal activity against promastigotes (IC
: 6.2 μg/ml) and amastigotes (IC
: 10.87 μg/ml) of Leishmania tropica. Brine shrimp lethality was also indicated by bioinspired ZnO nanoparticles (IC
: 21.29 μg/ml).
Hemocompatible nature of bioinspired nanoparticles was revealed. Furthermore, the antioxidant activities were performed. In addition, significant protein kinase while insignificant alpha amylase inhibition were recorded.</description><identifier>ISSN: 1743-5889</identifier><identifier>EISSN: 1748-6963</identifier><identifier>DOI: 10.2217/nnm-2017-0124</identifier><identifier>PMID: 28699838</identifier><language>eng</language><publisher>England: Future Medicine Ltd</publisher><subject>Animals ; Anti-Infective Agents - chemical synthesis ; Anti-Infective Agents - pharmacology ; Antioxidants - chemistry ; Antioxidants - pharmacology ; Aqueous solutions ; Artemia ; Biocompatibility ; Biocompatible Materials - chemistry ; Biosynthesis ; Camellia - chemistry ; Cosmetics ; Cytotoxicity ; Enzyme Inhibitors ; Fourier transforms ; Humans ; Lasers ; Leishmania tropica - drug effects ; Leishmania tropica - metabolism ; Microbial Viability ; Molecular beam epitaxy ; Nanoparticles ; Nanoparticles - chemistry ; Particle Size ; Plant Extracts - chemistry ; Plant Extracts - pharmacology ; Protein Kinases - chemistry ; Quantum dots ; Spectrum analysis ; Surface Properties ; Zinc Oxide - chemical synthesis ; Zinc oxides</subject><ispartof>Nanomedicine (London, England), 2017-08, Vol.12 (15), p.1767-1789</ispartof><rights>Copyright Future Medicine Ltd Aug 2017</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c321t-4baa4080945aa059a82099cbd91221cf6b57792537581b27a617230928b1f863</citedby><cites>FETCH-LOGICAL-c321t-4baa4080945aa059a82099cbd91221cf6b57792537581b27a617230928b1f863</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28699838$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Khalil, Ali Talha</creatorcontrib><creatorcontrib>Ovais, Muhammad</creatorcontrib><creatorcontrib>Ullah, Ikram</creatorcontrib><creatorcontrib>Ali, Muhammad</creatorcontrib><creatorcontrib>Shinwari, Zabta Khan</creatorcontrib><creatorcontrib>Khamlich, Saleh</creatorcontrib><creatorcontrib>Maaza, Malik</creatorcontrib><title>Sageretia thea (Osbeck.) mediated synthesis of zinc oxide nanoparticles and its biological applications</title><title>Nanomedicine (London, England)</title><addtitle>Nanomedicine (Lond)</addtitle><description>To investigate the physical and biological properties of bioinspired zinc oxide (ZnO) nanoparticles via aqueous leaf extracts of Sageretia thea.
Nanoparticles of size approximately 12.4 nm were extensively characterized. In vitro antimicrobial, cytotoxic, biocompatible and enzyme inhibition assays were performed.
Significant antimicrobial activities with and without UV illumination are reported. Bioinspired ZnO nanoparticles were found effective against fungal strains. MTT assay was performed to check the leishmanicidal activity against promastigotes (IC
: 6.2 μg/ml) and amastigotes (IC
: 10.87 μg/ml) of Leishmania tropica. Brine shrimp lethality was also indicated by bioinspired ZnO nanoparticles (IC
: 21.29 μg/ml).
Hemocompatible nature of bioinspired nanoparticles was revealed. Furthermore, the antioxidant activities were performed. In addition, significant protein kinase while insignificant alpha amylase inhibition were recorded.</description><subject>Animals</subject><subject>Anti-Infective Agents - chemical synthesis</subject><subject>Anti-Infective Agents - pharmacology</subject><subject>Antioxidants - chemistry</subject><subject>Antioxidants - pharmacology</subject><subject>Aqueous solutions</subject><subject>Artemia</subject><subject>Biocompatibility</subject><subject>Biocompatible Materials - chemistry</subject><subject>Biosynthesis</subject><subject>Camellia - chemistry</subject><subject>Cosmetics</subject><subject>Cytotoxicity</subject><subject>Enzyme Inhibitors</subject><subject>Fourier transforms</subject><subject>Humans</subject><subject>Lasers</subject><subject>Leishmania tropica - drug effects</subject><subject>Leishmania tropica - metabolism</subject><subject>Microbial Viability</subject><subject>Molecular beam epitaxy</subject><subject>Nanoparticles</subject><subject>Nanoparticles - chemistry</subject><subject>Particle Size</subject><subject>Plant Extracts - chemistry</subject><subject>Plant Extracts - pharmacology</subject><subject>Protein Kinases - chemistry</subject><subject>Quantum dots</subject><subject>Spectrum analysis</subject><subject>Surface Properties</subject><subject>Zinc Oxide - chemical synthesis</subject><subject>Zinc oxides</subject><issn>1743-5889</issn><issn>1748-6963</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpdkUtPwzAQhC0EolA4ckWWuJRDih952EdU8ZIq9UDv1sZxiktqhziVKL8ehxYOnHak_TTanUHoipIpY7S4c26TMEKLhFCWHqEzWqQiyWXOj380TzIh5Aidh7AmJBOMklM0YiKXUnBxhlavsDKd6S3g_s0AnixCafT79BZvTGWhNxUOOxdXwQbsa_xlncb-01YGO3C-ha63ujEBg6uw7QMurW_8ympoMLRtE0VvvQsX6KSGJpjLwxyj5ePDcvaczBdPL7P7eaI5o32SlgApEUSmGQDJJAhGpNRlJWn8Vtd5mRWFZBkvMkFLVkBOC8aJZKKktcj5GE32tm3nP7Ym9GpjgzZNA874bVBU0vg2p2ka0Zt_6NpvOxePUyzekosIDVSyp3TnQ-hMrdrObqDbKUrUUICKBaihADUUEPnrg-u2jAn-0b-J82_XnH_s</recordid><startdate>201708</startdate><enddate>201708</enddate><creator>Khalil, Ali Talha</creator><creator>Ovais, Muhammad</creator><creator>Ullah, Ikram</creator><creator>Ali, Muhammad</creator><creator>Shinwari, Zabta Khan</creator><creator>Khamlich, Saleh</creator><creator>Maaza, Malik</creator><general>Future Medicine Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>EHMNL</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>201708</creationdate><title>Sageretia thea (Osbeck.) mediated synthesis of zinc oxide nanoparticles and its biological applications</title><author>Khalil, Ali Talha ; Ovais, Muhammad ; Ullah, Ikram ; Ali, Muhammad ; Shinwari, Zabta Khan ; Khamlich, Saleh ; Maaza, Malik</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c321t-4baa4080945aa059a82099cbd91221cf6b57792537581b27a617230928b1f863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Animals</topic><topic>Anti-Infective Agents - chemical synthesis</topic><topic>Anti-Infective Agents - pharmacology</topic><topic>Antioxidants - chemistry</topic><topic>Antioxidants - pharmacology</topic><topic>Aqueous solutions</topic><topic>Artemia</topic><topic>Biocompatibility</topic><topic>Biocompatible Materials - chemistry</topic><topic>Biosynthesis</topic><topic>Camellia - chemistry</topic><topic>Cosmetics</topic><topic>Cytotoxicity</topic><topic>Enzyme Inhibitors</topic><topic>Fourier transforms</topic><topic>Humans</topic><topic>Lasers</topic><topic>Leishmania tropica - drug effects</topic><topic>Leishmania tropica - metabolism</topic><topic>Microbial Viability</topic><topic>Molecular beam epitaxy</topic><topic>Nanoparticles</topic><topic>Nanoparticles - chemistry</topic><topic>Particle Size</topic><topic>Plant Extracts - chemistry</topic><topic>Plant Extracts - pharmacology</topic><topic>Protein Kinases - chemistry</topic><topic>Quantum dots</topic><topic>Spectrum analysis</topic><topic>Surface Properties</topic><topic>Zinc Oxide - chemical synthesis</topic><topic>Zinc oxides</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Khalil, Ali Talha</creatorcontrib><creatorcontrib>Ovais, Muhammad</creatorcontrib><creatorcontrib>Ullah, Ikram</creatorcontrib><creatorcontrib>Ali, Muhammad</creatorcontrib><creatorcontrib>Shinwari, Zabta Khan</creatorcontrib><creatorcontrib>Khamlich, Saleh</creatorcontrib><creatorcontrib>Maaza, Malik</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>UK & Ireland Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Nanomedicine (London, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Khalil, Ali Talha</au><au>Ovais, Muhammad</au><au>Ullah, Ikram</au><au>Ali, Muhammad</au><au>Shinwari, Zabta Khan</au><au>Khamlich, Saleh</au><au>Maaza, Malik</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sageretia thea (Osbeck.) mediated synthesis of zinc oxide nanoparticles and its biological applications</atitle><jtitle>Nanomedicine (London, England)</jtitle><addtitle>Nanomedicine (Lond)</addtitle><date>2017-08</date><risdate>2017</risdate><volume>12</volume><issue>15</issue><spage>1767</spage><epage>1789</epage><pages>1767-1789</pages><issn>1743-5889</issn><eissn>1748-6963</eissn><abstract>To investigate the physical and biological properties of bioinspired zinc oxide (ZnO) nanoparticles via aqueous leaf extracts of Sageretia thea.
Nanoparticles of size approximately 12.4 nm were extensively characterized. In vitro antimicrobial, cytotoxic, biocompatible and enzyme inhibition assays were performed.
Significant antimicrobial activities with and without UV illumination are reported. Bioinspired ZnO nanoparticles were found effective against fungal strains. MTT assay was performed to check the leishmanicidal activity against promastigotes (IC
: 6.2 μg/ml) and amastigotes (IC
: 10.87 μg/ml) of Leishmania tropica. Brine shrimp lethality was also indicated by bioinspired ZnO nanoparticles (IC
: 21.29 μg/ml).
Hemocompatible nature of bioinspired nanoparticles was revealed. Furthermore, the antioxidant activities were performed. In addition, significant protein kinase while insignificant alpha amylase inhibition were recorded.</abstract><cop>England</cop><pub>Future Medicine Ltd</pub><pmid>28699838</pmid><doi>10.2217/nnm-2017-0124</doi><tpages>23</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1743-5889 |
| ispartof | Nanomedicine (London, England), 2017-08, Vol.12 (15), p.1767-1789 |
| issn | 1743-5889 1748-6963 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1918383144 |
| source | PubMed (Medline); MEDLINE |
| subjects | Animals Anti-Infective Agents - chemical synthesis Anti-Infective Agents - pharmacology Antioxidants - chemistry Antioxidants - pharmacology Aqueous solutions Artemia Biocompatibility Biocompatible Materials - chemistry Biosynthesis Camellia - chemistry Cosmetics Cytotoxicity Enzyme Inhibitors Fourier transforms Humans Lasers Leishmania tropica - drug effects Leishmania tropica - metabolism Microbial Viability Molecular beam epitaxy Nanoparticles Nanoparticles - chemistry Particle Size Plant Extracts - chemistry Plant Extracts - pharmacology Protein Kinases - chemistry Quantum dots Spectrum analysis Surface Properties Zinc Oxide - chemical synthesis Zinc oxides |
| title | Sageretia thea (Osbeck.) mediated synthesis of zinc oxide nanoparticles and its biological applications |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T05%3A54%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Sageretia%20thea%20(Osbeck.)%20mediated%20synthesis%20of%20zinc%20oxide%20nanoparticles%20and%20its%20biological%20applications&rft.jtitle=Nanomedicine%20(London,%20England)&rft.au=Khalil,%20Ali%20Talha&rft.date=2017-08&rft.volume=12&rft.issue=15&rft.spage=1767&rft.epage=1789&rft.pages=1767-1789&rft.issn=1743-5889&rft.eissn=1748-6963&rft_id=info:doi/10.2217/nnm-2017-0124&rft_dat=%3Cproquest_cross%3E1918383144%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2321681444&rft_id=info:pmid/28699838&rfr_iscdi=true |