Identification of genetic correlates of response to Risperidone: Findings of a multicentric schizophrenia study from India

•Genetic polymorphisms for dopaminergic (DRD2, Taq1D; rs180498) and serotonergic (5HT2A, 516 C>T; rs6305) significantly differentiates the patients suffering from schizophrenia who respond/do not respond to treatment with risperidone.•Age and gender adjusted odds of responding to treatment with r...

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Veröffentlicht in:	Asian journal of psychiatry 2017-10, Vol.29, p.174-182
Hauptverfasser:	Kaur, Gurjit, Gupta, Deepti, Chavan, Bir Singh, Sinhmar, Vikas, Prasad, Rajendra, Tripathi, Adarsh, Garg, P.D., Gupta, Rajiv, Khurana, Hitesh, Gautam, Shiv, Margoob, Mushtaq Ahmed, Aneja, Jitender
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT2A Adult Alleles Antipsychotic Agents - therapeutic use CYP2D6 Cytochrome P-450 CYP2D6 - genetics DRD2 Female Gene Frequency Genetic polymorphism Humans India Male Middle Aged Pharmacogenetics Polymorphism, Single Nucleotide Prospective Studies Receptor, Serotonin, 5-HT2A - genetics Receptors, Dopamine D2 - genetics Risperidone Risperidone - therapeutic use Schizophrenia Schizophrenia - drug therapy Schizophrenia - genetics Treatment Outcome
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