Regulation of body size in Caenorhabditis elegans: effects of environmental factors and the nervous system

Body size is one of the basic traits of animals and is regulated to adapt to the environment. Animals perceive environmental stimuli with sensory neurons, and signals from the nervous system alter the size of organs, thus regulating body size. The model animal Caenorhabditis elegans is particularly...

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Veröffentlicht in:The International journal of developmental biology 2017, Vol.61 (6-7), p.367-374
Hauptverfasser: Nagashima, Takashi, Ishiura, Shoichi, Suo, Satoshi
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container_title The International journal of developmental biology
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creator Nagashima, Takashi
Ishiura, Shoichi
Suo, Satoshi
description Body size is one of the basic traits of animals and is regulated to adapt to the environment. Animals perceive environmental stimuli with sensory neurons, and signals from the nervous system alter the size of organs, thus regulating body size. The model animal Caenorhabditis elegans is particularly suited for genetic analysis of body size regulation, and has already contributed to the elucidation of various genetic pathways that regulate body size. In this review, we summarize the available literature regarding environmental factors that regulate body size and the role of the nervous system in such regulation. We discuss in detail a recent report on body size regulation by the neurotransmitter, dopamine.
doi_str_mv 10.1387/ijdb.160352ss
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subjects Animals
Body Size
Caenorhabditis elegans - growth & development
Caenorhabditis elegans - metabolism
Caenorhabditis elegans Proteins - metabolism
Environment
Nervous System - growth & development
Nervous System - metabolism
Signal Transduction
title Regulation of body size in Caenorhabditis elegans: effects of environmental factors and the nervous system
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