Pharmacological analysis of the inhibition produced by moxonidine and agmatine on the vasodepressor sensory CGRPergic outflow in pithed rats

Calcitonin gene-related peptide (CGRP) plays a role in several (patho)physiological functions, and modulation of its release is considered a therapeutic target. In this respect, electrical spinal (T9-T12) stimulation of the perivascular sensory outflow in pithed rats produces vasodepressor response...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of pharmacology 2017-10, Vol.812, p.97-103
Hauptverfasser:	Rubio-Beltrán, Eloísa, Labastida-Ramírez, Alejandro, Hernández-Abreu, Oswaldo, MaassenVanDenBrink, Antoinette, Villalón, Carlos M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agmatine Agmatine - pharmacology Animals Calcitonin Gene-Related Peptide - metabolism Dose-Response Relationship, Drug Electric Stimulation Hemodynamics - drug effects Imidazoles - pharmacology Imidazoline receptors Male Moxonidine Pithed rat Rats Rats, Wistar Sympathetic Nervous System - drug effects Sympathetic Nervous System - physiology Vasodepressor sensory CGRPergic outflow
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!