Current understanding and management of pulmonary Langerhans cell histiocytosis

Pulmonary Langerhans cell histiocytosis (PLCH) is a diffuse lung disease that usually affects young adult smokers. PLCH affects different lung compartments; bronchiolar, interstitial and pulmonary vascular dysfunction may coexist to varying extents, resulting in diverse phenotypes. Analyses of PLCH...

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Veröffentlicht in:	Thorax 2017-10, Vol.72 (10), p.937-945
Hauptverfasser:	Vassallo, Robert, Harari, Sergio, Tazi, Abdellatif
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Autoimmune diseases Dendritic cells Disease Progression Histiocytosis, Langerhans-Cell - etiology Histiocytosis, Langerhans-Cell - genetics Histiocytosis, Langerhans-Cell - therapy Humans Lung diseases Lung Diseases - etiology Lung Diseases - genetics Lung Diseases - therapy Lymphocytes Mutation Pathogenesis Phenotype Pulmonary hypertension Smoking - adverse effects
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