Remyelination therapies: a new direction and challenge in multiple sclerosis

Key Points People with multiple sclerosis exhibit variable degrees of remyelination. Individuals with greater capacity to remyelinate seem to have less clinical disability, thereby fuelling the research to find remyelination therapeutics for multiple sclerosis. The biology of remyelination and its s...

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Veröffentlicht in:	Nature reviews. Drug discovery 2017-09, Vol.16 (9), p.617-634
Hauptverfasser:	Plemel, Jason R., Liu, Wei-Qiao, Yong, V. Wee
Format:	Artikel
Sprache:	eng
Schlagworte:	631/154 631/378/2606 692/699/375/1666 Animals Biomedicine Biotechnology Cancer Research Care and treatment Clinical trials Conversion therapy Disease Models, Animal Drug Evaluation, Preclinical Genetic aspects Humans Medicinal Chemistry Models, Biological Molecular Medicine Multiple sclerosis Multiple Sclerosis - drug therapy Myelin Sheath - drug effects Myelin Sheath - physiology Myelination Pharmacology/Toxicology Physiological aspects review-article
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