Adverse effects of immune checkpoint inhibitors used to treat melanoma and other cancer

Monoclonal antibodies targeted against the immune checkpoint molecules CTLA-4 and PD-1 have recently obtained approval for the treatment of metastatic melanoma and advanced/refractory non small-cell lung cancers and metastatic renal cancer. Besides their efficacy profile, these immune targeted agent...

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Veröffentlicht in:La Presse médicale (1983) 2017-09, Vol.46 (9), p.808-817
Hauptverfasser: Jacquin-Porretaz, Claire, Nardin, Charlée, Puzenat, Eve, Roche-Kubler, Blandine, Aubin, François
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Sprache:fre
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