Microenvironment and Dose-Delivery-Dependent Response after Exposure to Ionizing Radiation in Human Colorectal Cancer Cell Lines

A significant body of knowledge about radiobiology is based on studies of single dose cellular irradiation, despite the fact that conventional clinical applications using dose fractionation. In addition, cellular radiation response strongly depends on cell–cell and cell–extracellular matrix (ECM) in...

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Veröffentlicht in:	Radiation research 2017-09, Vol.188 (3), p.291-302
Hauptverfasser:	Stankevicius, Vaidotas, Vasauskas, Gintautas, Rynkeviciene, Ryte, Venius, Jonas, Pasukoniene, Vita, Aleknavicius, Eduardas, Suziedelis, Kestutis
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Survival - radiation effects Colorectal Neoplasms - metabolism Colorectal Neoplasms - radiotherapy Dose Hypofractionation Extracellular Matrix - metabolism Extracellular Matrix - radiation effects Extracellular Matrix Proteins - metabolism HT29 Cells Humans Neoplasm Proteins - metabolism Radiotherapy Dosage REGULAR ARTICLES Space life sciences Treatment Outcome Tumor Microenvironment - radiation effects
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