Microfluidic technologies for anticancer drug studies

•3D cell systems show high resistance to cytotoxic treatment compared with 2D models.•Microfluidic systems allow cost-effective analysis of cytotoxic drugs.•Integration of multiple microfluidic systems can recreate physiological cell–cell interactions.•Microfluidic chips allow integration of chemica...

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Veröffentlicht in:	Drug discovery today 2017-11, Vol.22 (11), p.1654-1670
Hauptverfasser:	Valente, Karolina P., Khetani, Sultan, Kolahchi, Ahmad R., Sanati-Nezhad, Amir, Suleman, Afzal, Akbari, Mohsen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - pharmacology Cell Culture Techniques - methods Drug Design Humans Lab-On-A-Chip Devices Microfluidics - methods Models, Biological Neoplasms - drug therapy Neoplasms - pathology
Online-Zugang:	Volltext
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