Ceruloplasmin inhibits the production of extracellular hepatitis B virions by targeting its middle surface protein

Ceruloplasmin (CP) is mainly synthesized by hepatocytes and plays an essential role in iron metabolism. Previous reports have shown that CP levels correlate negatively with disease progression in patients with chronic hepatitis B. However, the function of CP in the hepatitis B virus (HBV) life cycle...

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Veröffentlicht in:	Journal of general virology 2017-06, Vol.98 (6), p.1410-1421
Hauptverfasser:	Zhao, Kaitao, Wu, Chunchen, Yao, Yongxuan, Cao, Liang, Zhang, Zhenhua, Yuan, Yifei, Wang, Yun, Pei, Rongjuan, Chen, Jizheng, Hu, Xue, Zhou, Yuan, Lu, Mengji, Chen, Xinwen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cell Line Ceruloplasmin - analysis Ceruloplasmin - metabolism Female Hepatitis B Surface Antigens - metabolism Hepatitis B virus - growth & development Hepatitis B virus - immunology Hepatitis B, Chronic - virology Hepatocytes - virology Humans Male Middle Aged Protein Interaction Mapping
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