High, but not low, exercise volume shifts the balance of renin-angiotensin system toward ACE2/Mas receptor axis in skeletal muscle in obese rats

Metabolic syndrome is a cluster of metabolic risk factors that is linked to central obesity, elevated blood pressure, insulin resistance (IR), and dyslipidemia, where the renin-angiotensin system (RAS) may provide a link among them. This study aimed to evaluate volume exercise effects comparing low...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2017-10, Vol.313 (4), p.E473-E482
Hauptverfasser:	Frantz, Eliete Dalla Corte, Giori, Isabele Gomes, Machado, Marcus Vinícius, Magliano, D'Angelo Carlo, Freitas, Fernanda Marques, Andrade, Mariana Sodré Boêta, Vieira, Aline Bomfim, Nóbrega, Antonio Claudio Lucas, Tibiriçá, Eduardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorptiometry, Photon ACE2 Angiotensin Angiotensin II Angiotensin-converting enzyme 2 Animals Axes (reference lines) Blood Glucose Blood Pressure Body Composition Body mass Body Weight Cholesterol - metabolism Cytokines Cytokines - metabolism Diet Diet, High-Fat Dyslipidemia Exercise Exhaustion Glucose Glucose metabolism Glucose tolerance Glucose Tolerance Test Heart rate Immunoblotting Inflammation Insulin Insulin - metabolism Interleukin-6 - metabolism Intra-Abdominal Fat Leptin Leptin - metabolism Lipid Metabolism Lipids Male Metabolic disorders Metabolic syndrome Muscle, Skeletal - metabolism Muscles Musculoskeletal system Obesity Physical Conditioning, Animal - methods Physical training Proto-Oncogene Proteins - metabolism Rats Rats, Inbred WKY Receptor, Angiotensin, Type 1 - metabolism Receptors, G-Protein-Coupled - metabolism Renin Renin-Angiotensin System Risk analysis Risk factors Rodents Signaling Skeletal muscle Treadmills Triglycerides - metabolism Tumor Necrosis Factor-alpha - metabolism
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