The Neuronal Adaptor Protein X11α Reduces Aβ Levels in the Brains of Alzheimer's APPswe Tg2576 Transgenic Mice

Increased production and deposition of the 40-42-amino acid β-amyloid peptide (Aβ) is believed to be central to the pathogenesis of Alzheimer's disease. Aβ is derived from the amyloid precursor protein (APP), but the mechanisms that regulate APP processing to produce Aβ are not fully understood...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of biological chemistry 2003-11, Vol.278 (47), p.47025-47029
Hauptverfasser:	Lee, Ju-Hyun, Lau, Kwok-Fai, Perkinton, Michael S., Standen, Claire L., Shemilt, Stephen J.A., Mercken, Luc, Cooper, Jonathan D., McLoughlin, Declan M., Miller, Christopher C.J.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!