Additional Improvements in Clinical Response From Adjuvant Biologic Response Modifiers in Adults With Moderate to Severe Systemic Lupus Erythematosus Despite Immunosuppressive Agents: A Systematic Review and Meta-analysis

The role of biologic disease-modifying drugs in patients with systemic lupus erythematosus (SLE) remains controversial. Following systematic review and meta-analysis protocol, we searched PubMed, EMBASE, Cochrane Library, and ClinicalTrials.gov in January 2017 to identify all studies of people with...

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Veröffentlicht in:	Clinical therapeutics 2017-07, Vol.39 (7), p.1479-1506.e45
Hauptverfasser:	Shamliyan, Tatyana A., Dospinescu, Paula
Format:	Artikel
Sprache:	eng
Schlagworte:	abatacept Adjuvants Adjuvants, Immunologic - therapeutic use Adult Adults Arthritis Autoimmune diseases belimumab Biological effects blisibimod Chronic conditions Clinical trials Criteria Documents Drugs Evaluation Grading Humans Immune system Immunosuppression Immunosuppressive agents Immunosuppressive Agents - therapeutic use Immunotherapy Libraries Literature reviews Lupus Lupus Erythematosus, Systemic - drug therapy Lupus nephritis Medical libraries Meta-analysis Monoclonal antibodies Mortality Nephritis Observational Studies as Topic Patients Quality Randomized Controlled Trials as Topic Renal function rigerimod Risk Rituximab Side effects Software Statistical analysis Systematic review Systemic lupus erythematosus Treatment Outcome
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