Transcription‐dependent association of HDAC2 with active chromatin

Histone deacetylase 2 (HDAC2) catalyzes deacetylation of histones at the promoter and coding regions of transcribed genes and regulates chromatin structure and transcription. To explore the role of HDAC2 and phosphorylated HDAC2 in gene regulation, we studied the location along transcribed genes, th...

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Veröffentlicht in:	Journal of cellular physiology 2018-02, Vol.233 (2), p.1650-1657
Hauptverfasser:	Jahan, Sanzida, Sun, Jian‐Min, He, Shihua, Davie, James R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Animals Chickens Chromatin Chromatin - genetics Chromatin - metabolism Chromatin Assembly and Disassembly chromatin fractionation Deacetylation DNA-directed RNA polymerase Elongation Erythrocytes Erythrocytes - enzymology Gene expression Gene regulation Genes HDAC2 protein histone acetylation Histone deacetylase Histone Deacetylase 2 - genetics Histone Deacetylase 2 - metabolism Histones Phosphorylation Promoter Regions, Genetic Protein Binding Proteins Recruitment Ribonucleic acid RNA RNA binding protein RNA polymerase RNA polymerase II RNA Polymerase II - genetics RNA Polymerase II - metabolism RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism RNA‐protein interaction Transcription Transcription Factors - genetics Transcription Factors - metabolism Transcription, Genetic
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