Alginate hydrogel improves anti-angiogenic bevacizumab activity in cancer therapy

[Display omitted] Anti-vascular endothelial growth factor (anti-VEGF) therapy applied to solid tumors is a promising strategy, yet, the challenge to deliver these agents at high drug concentrations together with the maintenance of therapeutic doses locally, at the tumor site, minimizes its benefits....

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Veröffentlicht in:European journal of pharmaceutics and biopharmaceutics 2017-10, Vol.119, p.271-282
Hauptverfasser: Ferreira, Natália N., M.B. Ferreira, Leonardo, Miranda-Gonçalves, Vera, Reis, Rui M., Seraphim, Thiago V., Borges, Júlio César, Baltazar, Fátima, Gremião, Maria Palmira D.
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Sprache:eng
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