Bronchoprotective tolerance with indacaterol is not modified by concomitant tiotropium in persistent asthma

Summary Background Tiotropium is a long acting muscarinic antagonist (LAMA), licensed as triple therapy with inhaled corticosteroid and long‐acting beta‐agonist (ICS/LABA). There may be a synergistic benefit between LAMA and LABA as a consequence of receptor cross‐talk, which in turn could modify be...

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Veröffentlicht in:	Clinical and experimental allergy 2017-10, Vol.47 (10), p.1239-1245
Hauptverfasser:	Jabbal, S., Manoharan, A., Lipworth, B. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine receptors (muscarinic) airway Asthma Corticosteroids hyperresponsiveness long acting beta 2 agonist long acting muscarinic antagonist Mannitol Respiratory tract Salbutamol Smoking
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