TEL, a Putative Tumor Suppressor, Induces Apoptosis and Represses Transcription of Bcl-X sub(L)

The ETS family transcriptional repressor TEL is frequently disrupted by chromosomal translocations, including the t(12; 21) in which the second allele of TEL is deleted in up to 90% of the cases. Consistent with its role as a putative tumor suppressor, TEL expression inhibits colony formation by Ras...

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Veröffentlicht in:	The Journal of biological chemistry 2003-11, Vol.278 (47), p.46378-46386
Hauptverfasser:	Irvin, B J, Wood, L D, Wang, L, Fenrick, R, Sansam, C G, Packham, G, Kinch, M, Yang, E, Hiebert, S W
Format:	Artikel
Sprache:	eng
Schlagworte:	Ras gene TEL gene
Online-Zugang:	Volltext
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