Hwangryunhaedoktang exerts anti-inflammation on LPS-induced NO production by suppressing MAPK and NF-κB activation in RAW264.7 macrophages

OBJECTIVE： This study aimed to evaluate whether Hwangryunhaedoktang （HHT）, a herbal compound, has an inhibitory effect on lipopolysaccharide （LPS）-induced inflammation in RAW264.7 macrophages. METHODS： The effects of HHT were evaluated by confirming nitric oxide （NO） production and expression of ind...

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Veröffentlicht in:	Journal of integrative medicine 2017-07, Vol.15 (4), p.326-336
Hauptverfasser:	Han, Byung Hyuk, Lee, Yun Jung, Yoon, Jung Joo, Choi, Eun Sik, Namgung, Seung, Jin, Xian Jun, Jeong, Da Hye, Kang, Dae Gill, Lee, Ho Sub
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology inflammation iNOS Interleukin-6 - secretion lipopolysaccharide Lipopolysaccharides - pharmacology LPS MAPK信号通路 medicine, Chinese traditional Mice mitogen-activated protein kinases Mitogen-Activated Protein Kinases - antagonists & inhibitors NF-kappa B - antagonists & inhibitors NF-kappa B - metabolism NF-κB nitric oxide Nitric Oxide - biosynthesis nuclear factor-κB Plant Extracts - pharmacology RAW 264.7 Cells Tumor Necrosis Factor-alpha - secretion tumor necrosis factor-α 丝裂原活化蛋白激酶巨噬细胞抗炎作用诱导型一氧化氮合酶
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