Mid-childhood outcomes after pre-viable preterm premature rupture of membranes

Objectives: Investigate cardiorespiratory outcomes in children surviving previable preterm premature rupture of membranes (PV-PPROM) before 22 weeks’ gestational age (GA) with minimum 2 weeks latency. STUDY Design: Single institution, follow-up of retrospectively identified children who were born af...

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Veröffentlicht in:Journal of perinatology 2017-09, Vol.37 (9), p.1053-1059
Hauptverfasser: Bentsen, M H, Satrell, E, Reigstad, H, Johnsen, S L, Vollsæter, M, Røksund, O D, Greve, G, Berg, A, Markestad, T, Halvorsen, T
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container_end_page 1059
container_issue 9
container_start_page 1053
container_title Journal of perinatology
container_volume 37
creator Bentsen, M H
Satrell, E
Reigstad, H
Johnsen, S L
Vollsæter, M
Røksund, O D
Greve, G
Berg, A
Markestad, T
Halvorsen, T
description Objectives: Investigate cardiorespiratory outcomes in children surviving previable preterm premature rupture of membranes (PV-PPROM) before 22 weeks’ gestational age (GA) with minimum 2 weeks latency. STUDY Design: Single institution, follow-up of retrospectively identified children who were born after PV-PPROM during 2000–2004, and individually matched preterm-born controls. Results: Eleven PV-PPROM and matched control children were included at mean age of 10.5 and 10.7 years. Rupture of membranes occurred at mean GA 18 2 and 27 6 weeks and birth at 28 3 and 28 6 weeks, respectively. Compared to controls, the PV-PPROM group had significantly poorer lung function, findings on echocardiography indicating mild pulmonary hypertension, and lower peak oxygen consumption. Chart reviews suggested more motor difficulties and a tendency towards more problems with learning and attention. Conclusion: The findings highlight a preterm-born sub-group in need of targeted long-term monitoring and possibly interventions regarding future cardiorespiratory and neurodevelopmental function.
doi_str_mv 10.1038/jp.2017.97
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STUDY Design: Single institution, follow-up of retrospectively identified children who were born after PV-PPROM during 2000–2004, and individually matched preterm-born controls. Results: Eleven PV-PPROM and matched control children were included at mean age of 10.5 and 10.7 years. Rupture of membranes occurred at mean GA 18 2 and 27 6 weeks and birth at 28 3 and 28 6 weeks, respectively. Compared to controls, the PV-PPROM group had significantly poorer lung function, findings on echocardiography indicating mild pulmonary hypertension, and lower peak oxygen consumption. Chart reviews suggested more motor difficulties and a tendency towards more problems with learning and attention. 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STUDY Design: Single institution, follow-up of retrospectively identified children who were born after PV-PPROM during 2000–2004, and individually matched preterm-born controls. Results: Eleven PV-PPROM and matched control children were included at mean age of 10.5 and 10.7 years. Rupture of membranes occurred at mean GA 18 2 and 27 6 weeks and birth at 28 3 and 28 6 weeks, respectively. Compared to controls, the PV-PPROM group had significantly poorer lung function, findings on echocardiography indicating mild pulmonary hypertension, and lower peak oxygen consumption. Chart reviews suggested more motor difficulties and a tendency towards more problems with learning and attention. 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subjects 692/308/409
692/499
Adult
Asthma
Blood pressure
Case-Control Studies
Child
Child development deviations
Childhood
Children
Children & youth
Complications and side effects
Developmental disabilities
Developmental Disabilities - epidemiology
Developmental Disabilities - etiology
Echocardiography
Female
Fetal Membranes, Premature Rupture
Fitness equipment
Follow-Up Studies
Gestational Age
Health risk assessment
Hospitals
Humans
Hypertension
Hypertension, Pulmonary - epidemiology
Hypertension, Pulmonary - etiology
Infant, Extremely Premature
Infant, Newborn
Intensive care
Latency
Lungs
Male
Medical records
Medicine
Medicine & Public Health
Membranes
Neonatal diseases
Obstetrics
original-article
Oxygen consumption
Oxygen Consumption - physiology
Patient outcomes
Pediatric research
Pediatric Surgery
Pediatrics
Physical therapy
Pregnancy
Premature rupture of membranes
Premature rupture of the membrane
Psychologists
Questionnaires
Respiratory function
Respiratory tract diseases
Retrospective Studies
Risk factors
Rupturing
Spirometry
Young Adult
title Mid-childhood outcomes after pre-viable preterm premature rupture of membranes
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