Biodegradable nanoparticles loaded with tetrameric melittin: preparation and membrane disruption evaluation

Melittin is the main component of bee venom consisting of 26 amino acids that has multiple effects, including antibacterial, antiviral and anti-inflammatory in various cell types. This peptide forms pores in biological membranes and triggers cell death. Therefore it has potential as an anti-cancer t...

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Veröffentlicht in:	General physiology and biophysics 2017-10, Vol.36 (4), p.373-381
Hauptverfasser:	Gonzalez-Horta, Azucena, Matamoros-Acosta, Arely, Chavez-Montes, Abelardo, Castro-Rios, Rocio, Lara-Arias, Jorge
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorbable Implants Delayed-Action Preparations - chemistry Diffusion Drug Design Liposomes - chemistry Melitten - administration & dosage Melitten - chemistry Membrane Fluidity - drug effects Nanocapsules - chemistry Nanocapsules - ultrastructure
Online-Zugang:	Volltext
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